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Translational Awards

Our Translational Award supports the early-stage development of new cardiovascular medicines and technologies. Find out more about the entry requirements, what’s included in the award and how to apply.

What is a Translational Award?

Translational Awards aim to progress the development of novel, innovative technologies towards benefits to human cardiovascular health. This scheme aims to drive fundamental cardiovascular discovery science along the translational pathway, first into human studies, through to phase II trials, towards patient benefit and/or commercialisation.

Proposals are expected to demonstrate a strong intellectual property position and a development proposition that could attract follow-on investment.

Projects can start and finish at any point along the translational pathway from initial development, through pre-clinical studies to early-phase clinical trials (up to and including phase II).

The finishing point must represent a significant scientific and/or value inflection point.

Please ensure you have read the information on this page before you start an application on the BHF Grant Management System (GMS).

Who can apply

The principal investigator will be a researcher working in an established research institution in the UK.

Individuals or teams from commercial organisations can apply as collaborators. 

Award budget

There is no limit on the amount of funding that can be applied for, but it should be justified and appropriate to the project.

Applicants are strongly encouraged to contact the BHF Translational Awards Team to discuss potential application.

Grant duration

Grants can last up to 3 years. Applicants must justify the timescale in the context of the proposed work. 

Projects should have clearly defined progression milestones (typically 3 to 5 milestones). Continued funding will be subject to the achievement of the relevant milestones.

We do not expect milestones to overlap. However, we may be prepared to consider overlapping milestones if they can be appropriately justified in exceptional circumstances.

Milestone success criteria

Your project’s milestones should be specific, measurable, achievable, relevant and timely (SMART), and detail any robust GO/NO-GO criteria, with an estimate of costs per milestone. Failure to meet these criteria will result in the early termination of the project.

It is advisable to structure all projects so that the critical question(s) are addressed as early as possible in the plan.

What we are looking for

Your project should:

  • be novel and inventive, addressing an unmet clinical need within the BHF remit
  • result in a product, technology or intervention that is ready for market development
  • be milestone-driven and have a credible delivery plan. 

The scheme covers any type of technology, including: 

  • novel therapeutics (small molecules or biologics)
  • drug repurposing
  • devices
  • surgical techniques
  • diagnostics
  • imaging technologies
  • digital solutions
  • cell therapy and regenerative medicine
  • early-phase clinical studies evaluating efficacy and safety.

The scheme does not support funding for investigative research focussed on open-ended questions and late-phase clinical trials. For those purposes, refer to either Project Grants or Clinical Studies funding schemes. 

Your application should provide clear and compelling information on the following:

  • an unmet healthcare need in heart and circulatory diseases
  • the advantages of the proposed technology over competing solutions
  • supporting proof of concept data
  • a structured project with no overlapping milestones
  • the intellectual property position
  • a proposed route to market and commercialisation
  • a strategy to navigate the relevant regulatory processes
  • long-term aims beyond the BHF Translational Award.

Work with your Institution's Technology Transfer Office (TTO) to develop the intellectual property strategy and commercial case for the application.
It’s important to consider the entire route to commercialisation for your technology and not just what may be funded by the particular Translational Award requested. Providing this information gives BHF and subsequent investors the confidence that the project is well designed and has the best chance of success.

The MHRA Innovation Office provides a free, informal service that can help with your regulatory queries. 

Please contact a member of the Research Translation Team if you’re unsure whether your research is at the appropriate stage of development or is eligible for funding.

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What we will fund

The award can be used flexibly. We will consider funding:

  • staff salaries (excluding PhD studentships)
  • consumables and essential research equipment
  • consultancy fees
  • outsourcing to contract research organisations
  • other fee-for service providers.

Outsourcing

We will consider providing funds to outsource project work to parties who undertake work on a contracted/out-sourced basis (e.g. contract research organisations (CROs)), subject to appropriate justification. Such parties may carry out specifically defined piece(s) of work on behalf of the investigators on a fee-for-service basis, with no potential claim as an inventor over any arising intellectual property.

Project management

Successful Translational Awards require efficient management and reporting to ensure that the project stays on target. An experienced project manager (salary grade 7 or 8) may be appointed for up to 0.2 FTE per annum to assist with this. They will be responsible for managing and coordinating project activities and communications within your organisation and between collaborators and sub-contractors, as well as regularly reporting to the BHF. 

More information on costing a grant.

Intellectual property management  

Where possible, intellectual property generated in the course of a BHF Translational Award project will be owned by the host institute, who will have the right to manage and exploit the project’s intellectual property. We expect you to have a strategy on how to protect, maintain and commercialise BHF-funded intellectual property and provide any costs for such activity.

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How to apply

Applications are assessed in a 2-stage process and must be completed in partnership with your Institution's TTO.

1. Submit your preliminary application

Applicants are required to submit a preliminary application which will be considered by the Translational Awards Committee. To access the Translational Award preliminary application form, please log in to the BHF Grants Management System.

For further guidance, refer to the Translational Award preliminary application sample. Following a successful preliminary application, the applicant will be invited to submit a full application form. 

2. Submit your full application

Full applications will be assessed by external peer reviewers and considered by the Translational Awards Committee. In addition, applicants will be invited to present and defend their research proposal at interview by the Translational Awards Committee. 

For further information, refer to the Translational Award full application sample.

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How long the application process takes

Please allow up to 10 months from the preliminary application submission to final funding decision.

How we assess your application

Preliminary applications are reviewed by members of the Translational Awards Commitee. 

Full applications are reviewed by independent expert reviewers and the Translational Awards Commitee. 

To better understand how proposals are assessed, please see BHF independent review guidelines and Translational Award review form.

The flowchart below shows the application journey:

Submission deadlines

There are 2 opportunities to submit preliminary or full applications each year:

  • preliminary application deadlines: 3 February 2027 and 4 August 2027

  • full application deadline: if your application is successful at the preliminary application stage, you will be informed directly of your full application deadline.

Applications must be received by 17:00 on the deadline date. Late submissions will not be considered.

We will acknowledge receipt of your application within 48 hours and advise when you can expect the result.

BHF reserve the right to change the deadline dates. We recommend that you check this page on a regular basis to take note of any changes.

Apply online

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BHF have partnered with Panacea Innovation to launch CardioStars, a unique programme that will equip researchers with the entrepreneurial and business skills to become the science innovators of tomorrow.

Find out how to apply for a research grant from BHF. You can also check our grant types and read through the relevant grant guidelines.

Clinical Trials Units (CTUs) are specialist units that help clinical researchers design, conduct, analyse and publish clinical trials. 

This page explains our policies on registering clinical trials on a database, how to manage a clinical trial and what the BHF expects with regard to data sharing for clinical trials.

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    Terms and conditions

    Our Translational Awards are subject to our Translational Award terms and conditions.

    Make sure you read and understand them fully before applying:

    Translational Award terms and conditions (PDF)