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Lacunar stroke is caused by damage to small blood vessels deep in the brain, and can ultimately lead to dementia. LACI-2 explored whether isosorbide mononitrate and cilostazol could be used to treat lacunar stroke.

Find out why you'd have a cardiac MRI scan, what happens during the scan, when you'll get results and where to get support.

RESEARCH

University of Southampton | Dr Hugh Gallagher

Chronic kidney disease (CKD) is common, particularly in the elderly. In some cases, it can advance into life-threatening kidney problems. But the greatest health threat to most people with CKD is that it significantly increases their risk o...

Clinical Study Grants support clinical trials and observational studies of specific patient groups. Previous awards have included a broad range of types and sizes of study, e.g. single centre pilot studies, large multi-centre trials, UK arms of international trials, sub-studies of existing trials.

RESEARCH

Imperial College London | Professor Anna Randi

The cells that make up the innermost lining of our blood vessels are called ‘endothelial cells’. They actively influence all sorts of functions including how permeable the vessels are, how they grow, and the tendency for blood to clot withi...

RESEARCH

University of Leicester | Professor Alison Goodall

Heart attacks are caused by a build up of atherosclerotic plaques in the arteries of the heart. The plaque can lead to restricted blood flow to the heart muscle, causing angina, or complete blockage of an artery, causing a heart attack. Pla...

RESEARCH

University of Cambridge | Professor Martin Bennett

Atherosclerosis occurs when fatty deposits, known as plaques, form in the walls of our blood vessels, such as the coronary supplying the heart. Some of these plaques can rupture and create a blood clot, which can cause a heart attack. Card...

RESEARCH

University of Nottingham | Professor Philip Bath

High blood pressure is common in people who have a stroke because of a blood clot or a bleed – called ischaemic or haemorrhagic stroke – and people are more likely to die or become disabled because of it. So far trials to lower blood pressu...

It has been a phenomenal year in the world of our research. From lifesaving dementia treatment to using fruit flies to better understand how the heart is formed, each discovery we fund helps take us a step closer to beating heartbreak forever. Here we take a look back at some of our research breakthroughs of 2023.

RESEARCH

University of Oxford | Professor Damian Tyler

Our hearts need to convert fuels (sugars and fats) into energy to enable them to beat. But we know that in heart disease, this process becomes altered, and the heart muscle cannot use fuel correctly. Dr Damian Tyler, from the University...