Aortic stiffness: mechanisms and clinical importance
The large arteries are elastic and they have an important role in buffering the swings of blood pressure that occur with each heartbeat. With age and in certain diseases, these arteries stiffen, leading to high blood pressure (hypertension), heart failure and increased risk of cardiovascular events, like angina, heart attack and stroke In this Senior Clinical Research Fellowship, Professor Ian Wilkinson at the University of Cambridge will investigate the mechanisms that lead to stiffened arteries so that new drugs can be developed to unstiffen arteries. He will also find out whether measuring how stiff arteries are in routine clinical practice alongside other measures like blood pressure and cholesterol will help target treatment at people most at risk of cardiovascular disease.
Project details
| Grant amount | £1,056,653 |
|---|---|
| Grant type | Fellowships |
| Application type | Senior Clinical Research Fellowship |
| Start Date | 01 March 2012 |
| Duration | 5 years |
| Reference | FS/12/8/29377 |
| Status | Complete |
