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Using stem cells to understand atherosclerosis

Professor Nicholas Mills (lead researcher)

University of Edinburgh

Start date: 02 February 2011 (Duration 5 years)

Derivation and characterisation of endothelial cells from induced pluripotent stem cells in patients with atherosclerosis

Damage to the cells that line our blood vessels (endothelial cells) result in formation of fatty deposits in the walls of the arteries (atherosclerosis) and can cause angina or a heart attack. In this fellowship, Dr Mills proposes to use stem cell technology to grow endothelial cells from patients with heart disease in the family. He will assess how these cells behave to understand the role of these cells in causing heart disease and determine whether these techniques might be used to grow blood vessel cells that could be used to repair damaged hearts in the future.

Project details

Grant amount £992,681
Grant type Fellowships
Application type Intermediate Clinical Research Fellowship
Start Date 02 February 2011
Duration 5 years
Reference FS/10/024/28266
Status Complete
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