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  • RESEARCH

    Addressing global gaps in knowledge about blood pressure treatment

    University of Oxford | Professor Kazem Rahimi

    Advances in research have shown that reducing high blood pressure with medicines can prevent heart disease and stroke. But there remain several gaps in our knowledge, including how blood pressure treatment affects other health issues, and w...

  • RESEARCH

    Understanding how blood vessel cells control blood clotting

    University of Leeds | Dr Lynn McKeown

    The formation of blood clots after damage to blood vessels is essential to prevent excessive bleeding. The first step in this process is the formation of a ‘plug’ of small blood cells called platelets. This is helped along by the release of...

  • RESEARCH

    Can microRNAs prevent complications after coronary artery stenting or bypass grafting?

    University of Glasgow | Professor Tomasz Guzik

    Patients who have life-saving surgery like a coronary artery bypass graft or a stent fitted, are unfortunately at higher risk of blood vessel blockage. To avoid this and maximise patient benefits, we need new treatments that prevent blood v...

  • RESEARCH

    How the kidney and carotid body interact to cause high blood pressure

    University of Exeter | Dr Maarten Koeners

    Dr Maarten Koeners from the University of Bristol wants to better understand the causes and mechanisms of hypertension, or high blood pressure, so we can develop more effective treatments. High blood pressure is a risk factor for several...

  • RESEARCH

    The role of haem in smooth muscle cells

    University of Leicester | Dr Noel W Davies

    Blood pressure is maintained by the contraction of smooth muscle cells (in blood vessels called vasoconstriction) which in turn depends on an electrical difference being maintained between the inside and outside of vascular smooth muscle (t...

  • RESEARCH

    Studying the role of insulin in macrophages

    University College London | Dr Ines Pineda Torra

    Dr Matthew Gage and his colleagues at University College London (UCL) are studying the role of insulin in immune cells called macrophages. These cells are involved in driving inflammation and, indirectly, in atherosclerosis – when blood ves...

  • RESEARCH

    Investigating alternatives to standard anticoagulant drugs

    University of Nottingham | Professor Jonas Emsley

    Anticoagulants are given to people to prevent deep vein thrombosis (a blood clot in a vein) or pulmonary embolism (a blood clot on the lungs) in people having surgery, or to prevent stroke in people with an abnormal heart rhythm, called atr...

  • RESEARCH

    Finding ways to repair damaged blood vessels in diabetes

    University of Leeds | Dr Richard Cubbon

    People with diabetes are at increased risk of heart attacks and strokes because of damaged blood vessels. This is in part because diabetes interferes with the body's repair of blood vessels, which may be because of the reduced action of a p...

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  • RESEARCH

    What makes partially-specialised cells in a growing embryo turn into blood vessel cells?

    University of East Anglia | Dr Gi Fay Mok

    In the growing embryo, stem cells (unspecialised cells) undergo rapid changes to become precursor cells (partially-specialised cells) and then specialised cells which perform specific functions. This process of cell differentiation is go...