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There are 3435 result(s) for coronary disease mortality
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RESEARCH
A cell skeleton that makes platelets stickyUniversity of Birmingham | Dr Steven Thomas
Dr Steven Thomas and his colleagues at the University of Birmingham are studying platelets, the small cells in the blood that respond to blood vessel damage by sticking to the vessel wall and to each other to form a blood clot and stop blee...
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RESEARCH
How a protein called Epac controls blood vessel diameterUniversity of Liverpool | Professor Caroline Dart
Dr Caroline Dart and colleagues at the University of Liverpool are studying how a protein called Epac controls blood vessel diameter. Blood vessels constantly change their diameter to match blood flow to the oxygen needs of tissues. These a...
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RESEARCH
What happens when atrial t-tubules disappear in heart failure?University of Manchester | Dr Katharine Dibb
People with heart failure are at higher risk of atrial fibrillation, an abnormal heart rhythm which greatly increases the risk of stroke. Dr Katharine Dibb and colleagues from the University of Manchester are researching the structure and f...
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RESEARCH
A trial of inhaled frusemide for advanced heart failureOxford Brookes University | Dr Shakeeb Moosavi
This clinical trial will investigate whether an inhaled form of frusemide provides relief from breathlessness in patients with advanced heart failure. People living with heart failure have symptoms such as breathlessness and tiredness b...
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RESEARCH
How does nitric oxide control the growth of new blood vessels in the eye?Queen's University Belfast | Dr Denise M McDonald
Dr Denise McDonald and Dr Anthony Collins from Queen’s University in Belfast, Northern Ireland, are investigating what controls growth of new blood vessels in the retina of the eye. Damage to these intricate vessels stops oxygen reaching th...
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RESEARCH
Hijacking the immune system to help prevent heart transplant rejectionKing's College London | Professor Giovanna Lombardi
When the heart becomes irreversibly damaged and fails, heart transplantation can be the only treatment option. However rejection of the donor heart by the immune system is a major problem. Immunosuppressant drugs have unpleasant side effect...
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RESEARCH
Designing a new heart patch to replace damaged heart muscle tissueUniversity of Cambridge | Professor Richard Farndale
Professor Richard Farndale is working out how to replace heart muscle tissue that has been irreversibly damaged, for instance, after a heart attack. Replacing this lost heart muscle could save many lives. In this project, Professor Farnd...
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RESEARCH
How proteins interact to cause blood clottingImperial College London | Dr Thomas McKinnon
Von Willebrand Factor (VWF) is a large blood protein that helps blood clotting by interacting with platelets when the blood vessels are injured. Platelets are a type of cell found in blood that help to plug a wound and prevent blood loss. H...
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RESEARCH
Do diseased hearts ‘deform’ in a different way to normal hearts?University of Oxford | Professor Vicente Grau
So the heart can pump blood and oxygen around the body effectively, its four chambers need to ‘deform’ and change shape. But when the heart muscle is damaged, such as after a heart attack, this process does not work and the heart does not p...
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RESEARCH
Is the epicardium a good target for new drugs to encourage heart repair?University of Oxford | Professor Paul Riley
Heart muscle cannot repair itself after injury, e.g. after a heart attack, so scientists are working to repair it using new heart muscle cells. BHF Professor Paul Riley and colleagues (University of Oxford and University College London) hav...