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RESEARCH
Does your weight affect your risk of heart surgery complications?University of Leicester | Professor Gavin Murphy
More than 35,000 people in the UK have heart surgery each year. Despite decades of research to improve outcomes, kidney and heart failure resulting from cardiac surgery still affects many patients. Professor Murphy’s team have shown that th...
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How inequalities contribute to heart and circulatory diseases
Data has been brought together across prevention, treatment and outcomes by levels of deprivation in England, outlining health inequalities.
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RESEARCH
Understanding how mast cells drive inflammation in blood vesselsQueen Mary, University of London | Professor Sussan Nourshargh
Inflammation is an essential part of the body’s defence system against viruses and bacteria. It is also an underlying cause of many heart and circulatory conditions like atherosclerosis. Atherosclerosis is the build-up of fatty substances i...
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RESEARCH
Understanding how oxidation of a protein called PKGI-alpha regulates the heartbeatUniversity of Manchester | Dr Luigi Venetucci
Each heartbeat consists of two phases: systole and diastole. During systole, heart muscle cells – cardiomyocytes – in the lower chambers of the heart contract (shorten) to pump blood out of the heart. During diastole, these lower chamber ca...
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RESEARCH
Developing a support programme to help people self-manage POTSUniversity of Warwick | Professor Kate Seers
Postural orthostatic tachycardia syndrome (POTS) is a condition where an abnormal increase in heart rate occurs after sitting or standing up. The syndrome is more common in women and is usually diagnosed between the ages of 17-35. POTS can ...
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RESEARCH
Swapping the heart’s energy source to treat heart failureUniversity of Oxford | Dr Oliver Rider
Regardless of cause, most heart diseases ultimately result in the heart being unable to pump out as much blood as a normal heart can, because it can’t contract as forcefully. To contract, the heart needs an energy source called ATP, and it’...
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RESEARCH
Investigating if MRI scanning can pick up prenatal brain defects in congenital heart diseaseUniversity of Sheffield | Professor Paul Griffiths
Structural problems in the developing heart (congenital heart disease) are amongst the most common birth defects in the UK. Many children with heart defects also have problems with the development of their brain, potentially causing difficu...
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RESEARCH
How to improve detection of atrial fibrillation with fitness bands and smart watchesUniversity of Cambridge | Dr Peter Charlton
Atrial fibrillation (AF) is a condition that causes irregular beating of the upper chambers of the heart. It increases the risk of stroke because a blood clot is more likely to form inside the heart and travel to the brain. AF is undiagnose...