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RESEARCH

Understanding the heart’s protective mechanisms to prevent heart failure

King's College London | Professor Ajay Shah

The focus of most heart failure treatments is to prevent further degeneration of the heart muscle, a process called adverse cardiac remodelling. There is, however, another type of remodelling that is good for the heart. Adaptive remodelling...

RESEARCH

What do bright spots in pregnancy scans tell us about children’s hearts?

Cardiff University | Dr Lisa Hurt

Each day in the UK, 12 babies are diagnosed with a heart defect that occurs as the baby develops in the womb. Pregnant women have an ultrasound scan when they are about 20 weeks pregnant, and nearly half of all serious heart defects are det...

Digital transformation within a clinical pathway

Created to support frontline healthcare staff, this resource shows how you can transform a clinical pathway using digital technology.

Patient and Public Involvement in Research

More information about how to involve patients and the public in your BHF-funded research

RESEARCH

Predicting and preventing hospitalisation in older people with heart disease

University of Manchester | Dr Adam Greenstein

Older people with heart disease are more likely to be admitted to hospital, and they often don’t do as well as younger, less frail people with the disease. In this fellowship, the fellow working with Dr Greenstein will investigate whether m...

RESEARCH

Understanding how oxidation of a protein called PKGI-alpha regulates the heartbeat

University of Manchester | Dr Luigi Venetucci

Each heartbeat consists of two phases: systole and diastole. During systole, heart muscle cells – cardiomyocytes – in the lower chambers of the heart contract (shorten) to pump blood out of the heart. During diastole, these lower chamber ca...

RESEARCH

How do omega-3 polyunsaturated fatty acids help to regulate blood pressure?

University of Reading | Dr Alister McNeish

Researchers at the University of Reading want to understand exactly how eating oily fish lowers blood pressure. Eating fish or taking fish oil supplements that are high in omega-3 has been shown to improve health. One way that fish oils ...

RESEARCH

How do heart muscle proteins change shape when the heart beats?

University of Bristol | Dr Danielle Paul

Proteins that make up heart muscle are arranged into structures called filaments. There are two types of filament: thick and thin. A protein called troponin is one of the main components of the thin filament and acts like a switch that turn...