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There are 4771 result(s) for living with long covid
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RESEARCH
Getting FISSical to understand heart muscle contractionKing's College London | Dr Yin Biao Sun
Each heart beat is triggered by a pulse of calcium in a heart muscle cell, and is driven at the molecular level by myosin and actin filaments sliding past each other and generating the force for contraction. Calcium triggers contraction by ...
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RESEARCH
Are chemical modifications of DNA involved in atherosclerosis?University of Bristol | Professor Andrew Newby
BHF Professor Andrew Newby has been awarded a three year grant to investigate the intricate processes that lead to plaque rupture in atherosclerosis. Atherosclerosis occurs when fatty deposits build up inside artery walls and harden, causin...
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RESEARCH
Developing a realistic computer model of abnormal heart rhythmsImperial College London | Dr Emmanuel Dupont
Dr Emmanuel Dupont and his team at Imperial College London are testing a new computer simulation, which would allow researchers to study abnormal heart rhythms. To beat regularly, the heart contracts in response to complex electrical ci...
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RESEARCH
Calcium uptake and heart relaxationImperial College London | Dr Alfonso De Simone
Calcium uptake in part of the heart muscle cell called the sarcoplasmic reticulum (SR) is crucial for the heart to relax, and is controlled by a protein called SERCA. In dilated cardiomyopathy, a cause of heart failure, SERCA either does n...
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RESEARCH
Using mathematics to predict the future for heart and circulatory diseaseUniversity of Oxford | Dr Peter Scarborough
BHF Intermediate Basic Science Research Fellow Dr Peter Scarborough is developing a new computer model that can predict heart and circulatory disease rates until 2030. In recent years the influence of risk factors for heart and circulato...
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RESEARCH
A sugar coated solution to stop blood vessel leakinessUniversity of Bristol | Dr Rebecca Foster
Cells that line the blood vessels (endothelial cells) are coated with a protective layer of sugars, called the glycocalyx, which helps the blood vessels to function normally. In health, vascular endothelial growth factor-A (VEGFA) is an im...
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RESEARCH
Finding out why statins sometimes cause muscle pain and weaknessUniversity of Leeds | Dr Sarah C Calaghan
Statins are medicines taken by millions of people in the UK as an effective way to lower their risk of having a heart attack or a stroke. However, some people who take statins develop a side-effect that causes muscle pain and weakness, part...
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RESEARCH
Understanding how the giant protein titin stretches and relaxesKing's College London | Professor Sergi Garcia-Manyes
During the course of a heartbeat, the muscle expands as the chambers fill with blood and then relaxes as the force of the contraction pushes oxygenated blood around the body. The versatile, elastic function of the heart is so important to i...
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RESEARCH
Studying a ‘radical’ enzyme linked to high blood pressureUniversity of Glasgow | Professor Rhian Touyz
This programme of research examines how an enzyme, Nox5, contributes to high blood pressure through the production of free radicals. High free radical levels may be due to increased production or to reduced antioxidants in cells. Although ...
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RESEARCH
Cardiac resynchronisation therapy: how it worksImperial College London | Professor Darrel Francis
Cardiac resynchronisation therapy (CRT) involves the implantation of a pacemaker device and is performed in certain heart failure patients to ensure the heartbeat maintains its rhythm. CRT has revolutionised treatment of some forms of heart...