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  • RESEARCH

    How the activated protein C pathway prevents blood clotting

    Imperial College London | Dr Josefin Ahnstrom

    Blood clotting is regulated by several different pathways, including a pathway that involves a protein called activated protein C, which prevents clotting. To work properly protein C relies on a partner, protein S. People who lack or have a...

  • RESEARCH

    Investigating why blood clots are more common in pregnant women who are overweight.

    University of Glasgow | Dr Catherine Bagot

    Blood clots in veins, while rare, are one of the main causes of death in pregnant women. Overweight pregnant women are at a greater risk of blood clots than pregnant women of a healthy weight, but the reasons why are not understood. Hig...

  • Special Recognition Award

    This award honours the contributions of individuals, groups, or organisations who have made a lasting, meaningful difference to those affected by cardiovascular disease.

  • Funding work in Northern Ireland

    Currently, there are over 225,000 people battling with cardiovascular disease (CVD) in Northern Ireland. Our local work and research is powered by your support. Every minute of your time and every donation will help make a difference to local people's lives.

  • RESEARCH

    Why do people with diabetes grow blood vessels more slowly?

    University of Nottingham | Professor David Bates

    Vascular disease, where blood vessels become blocked, is common in people with type 2 diabetes as they get older. Since it blocks the flow of oxygen to the limbs, it can cause painful legs, inability to walk or even lead to amputation. Scie...

  • RESEARCH

    A sugar coated solution to stop blood vessel leakiness

    University of Bristol | Dr Rebecca Foster

    Cells that line the blood vessels (endothelial cells) are coated with a protective layer of sugars, called the glycocalyx, which helps the blood vessels to function normally. In health, vascular endothelial growth factor-A (VEGFA) is an im...

  • RESEARCH

    Protecting leg muscles and blood vessels from the damaging effects of diabetes

    University of Bristol | Professor Paolo Madeddu

    Diabetes is a serious and common condition that occurs when there is too much sugar (glucose) in the blood because the body can’t use it or store it properly. Diabetes can damage the arteries and veins that supply blood to our legs. This ca...

  • Watch: Could fat in your bloodstream cause blood clots?

    BHF research is shedding more light on how fats in your blood could affect your health. Our animation explains Dr Alan Stewart's research.

  • Our impact on haemostasis and thrombosis research 

    BHF-funded research into haemostasis and thrombosis has helped us to learn more about our circulatory system. Discover the impact this research has had.

  • Stuart on being a defibrillator Guardian and saving his son's life

    When Stuart's child had a cardiac arrest, it was the last thing he thought would happen. Stuart talks about that day and his work as a defibrillator Guardian.