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A breakthrough in our understanding of Alzheimer’s disease has revealed changes to blood vessels in the brain, potentially presenting a path for developing new drugs to help fight the disease, according to research we funded and published in Proceedings of the National Academy of Sciences (PNAS).

RESEARCH

Oxford, University of | Richard McManus

People who have had a stroke or a ‘mini-stroke’ – known to doctors as a TIA - are at higher risk of a further stroke/TIA if their blood pressure is too high. Unfortunately, high blood pressure is common, and too often poorly controlled. Pre...

RESEARCH

University of Hull | Dr Simon Calaminus

Hull researchers are uncovering the role of zinc in platelets and bleeding. Zinc plays an important role in the body. Zinc deficiency exists in many health problems, and is linked to excess bleeding. It is not yet known exactly how a lac...

RESEARCH

University of Sheffield | Professor Sheila Francis

A partnership between Dr Sheila Francis at the University of Sheffield and Dr Emmanuel Pinteaux at the University of Manchester has been awarded nearly £300,000 over three years to investigate the role of interleukins in coronary heart dise...

Have you been prescribed ACE inhibitors? Read what they are, how they work, their possible side effects and more.

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RESEARCH

University College London | Professor Eric Brunner

In 1985 a major research study was launched, with the ambition of investigating the causes of social inequalities in health. The study, called Whitehall II, recruited 10,308 London civil servants aged 35- 55 and has followed them up with re...

RESEARCH

University of Sheffield | Professor Paul Evans

Atherosclerosis is the leading cause of death worldwide. It causes fatty deposits called plaques to build-up beneath the inner lining of arteries (the endothelium). If a plaque bursts, it can cause a blood clot to form. This can block the b...

RESEARCH

University of Sheffield | Professor Sheila Francis

Sheffield researchers will investigate if the vascular changes seen in the brain caused by atherosclerosis are similar to those found in vascular dementia, and if new treatments could help with both. Atherosclerosis refers to the build-u...