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There are 3447 result(s) for coronary disease mortality
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Can statins lower dementia risk?
We fact-check newspaper reports on a new study that suggest statins reduce the risk of dementia as well as lowering cholesterol.
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RESEARCH
Studying a protein that encourages new blood vessels to growUniversity of Birmingham | Dr Victoria Heath
Dr Victoria Heath’s PhD student is finding out how a protein called protocadherin 1 helps new blood vessels to form. When the blood supply to parts of the body becomes restricted because of blocked blood vessels, blood vessels need to grow ...
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RESEARCH
Finding the mechanisms that control thrombosisUniversity of Cambridge | Professor James Huntington
Professor James Huntington at the University of Cambridge is studying new ways to treat thrombosis, where blood clots form when they shouldn’t, which can lead to a heart attack or stroke. Blood needs to clot rapidly to protect us after inj...
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RESEARCH
Finding potential drugs to control blood vessel functionUniversity of Oxford | Dr Paolo Tammaro
Calcium-activated chloride channels (CaCCs) are one of a family of important molecules called ion channels, which are present on the surface of all cells. They are involved in several physiological processes, including the expansion and con...
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RESEARCH
How blood factors work together to prevent clottingImperial College London | Dr Josefin Ahnstrom
Dr Josefin Ahnstrom and colleagues at Imperial College London have been awarded a 3-year grant to investigate the components that prevent blood from clotting, including Tissue Factor Pathway Inhibitor (TFPI), protein S and factor V. They ai...
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RESEARCH
Promoting new blood vessel growth in people with limb ischaemiaKing's College London | Professor Bijan Modarai
In humans, ischaemia – lack of oxygen in the circulation – can cause peripheral arterial disease – which is common in elderly people, and can be very painful – and even cause gangrene and require limb amputation. Dr Bijan Modarai’s team fro...
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RESEARCH
Understanding how the giant protein titin stretches and relaxesKing's College London | Professor Sergi Garcia-Manyes
During the course of a heartbeat, the muscle expands as the chambers fill with blood and then relaxes as the force of the contraction pushes oxygenated blood around the body. The versatile, elastic function of the heart is so important to i...
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RESEARCH
Working out what controls the heart’s response to adrenalineUniversity of Dundee | Professor Michael L J Ashford
Dr William Fuller is studying the mechanisms that control how the heart responds to adrenaline, the hormone that increases the strength of the heartbeat. Caveolae are small pits in the cell membrane that bring proteins together so they c...
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RESEARCH
Does a protein called Piezo1 hold the key to preventing stiffening of the heart valves?Imperial College London | Dr Najma Latif
Heart valves are constantly subjected to mechanical forces such as pressure, bending and friction from blood flow, which can lead to stiffening of the valve – known as calcification. Although we know that cells that line the surface of hea...
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RESEARCH
Using sugar-coated proteins to trick the immune system in heart transplantsKing's College London | Professor Giovanna Lombardi
The success of heart transplants in people with heart failure is limited because of late-stage organ rejection and the side effects of giving people immunosuppressive drugs. Scientists are therefore looking for ways to adapt the immune sys...