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There are 3739 result(s) for coronary disease mortality
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RESEARCH
A potential new application for the drug Sulforadex – a treatment for Noonan syndromeKing's College London | Professor Philip Eaton
Noonan syndrome is a genetic disorder that affects up to 1 in 1,000 births and is known to cause heart conditions, learning problems and short stature. In half of people with Noonan syndrome, the genetic cause is a mutation in a gene called...
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RESEARCH
A clinical trial to find the best treatment for minor strokeUniversity of Glasgow | Professor Keith Muir
Around half of strokes have minor symptoms or appear to improve quickly (known as a transient ischaemic attack). However, about 1 in 3 of these minor strokes can lead to long-lasting disability. People who’ve had a minor stroke are not ...
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RESEARCH
New drugs to break the cycle of heart scarringUniversity of Bristol | Dr Mark Bond
The build-up of scar tissue in the heart (fibrosis) is a key process that contributes to heart failure. It is caused by an increased number of cells called fibroblasts, which lay together to form scar tissue. The result is that the heart wa...
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RESEARCH
Using artificial intelligence to predict the underlying causes of high blood pressureUniversity of Manchester | Professor Maciej Tomaszewski
High blood pressure (hypertension) is a major cause of heart attacks and strokes. Studies of the human genome have identified over a thousand differences between people’s DNA (genetic variants) that are associated with blood pressure. T...
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RESEARCH
A computer model to help doctors care for heart failure patientsUniversity of Oxford | Professor Kazem Rahimi
Supervised by Professor Kazem Rahimi, this PhD student is developing a new computer model to help doctors care for people with heart failure. Heart failure, when the heart cannot pump blood effectively around the body, severely impacts h...
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RESEARCH
Tracing early origins of heart development in the embryo to inform stem cell therapiesUniversity of Oxford | Professor Catherine Porcher
Development of a fully formed heart and circulation in the embryo requires the precise allocation of cells to the right place at the right time. Our understanding of these processes has improved in recent decades but the very earliest stage...
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RESEARCH
How SUMO wrestles heart injury after a heart attackUniversity of Bristol | Professor Jeremy Henley
Dr Jeremy Henley and colleagues at the University of Bristol have been awarded a grant to investigate how a protein called SUMO can help protect the heart from injury. The SUMO protein is attached to a specific protein in mitochondria, whic...
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RESEARCH
A protein WISP-1 may reduce the risk of aneurysm formationUniversity of Bristol | Professor Sarah Jane George
Professor Sarah Jane George and colleagues at the University of Bristol have been awarded a 3-year grant to demonstrate the role of a protein called WISP-1 in reducing the risk of aneurysm formation. An aneurysm is a localized, balloon-...
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RESEARCH
Improving patient outcome after transcatheter aortic valve replacement surgery for aortic stenosisUniversity College London | Professor Gaetano Burriesci
Dr Gaetano Burriesci has been awarded a PhD studentship to work out how to improve patient outcome following transcatheter aortic valve implantation (TAVI), an operation where a new valve is manoeuvred up the femoral artery and inserted ins...
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RESEARCH
How do potentially deadly aneurysms grow?University of Leicester | Professor Matthew Bown
<p>An abdominal aortic aneurysm (AAA) is a balloon-like swelling of the aorta, the body’s main blood vessel. If AAAs become large and burst, they can cause internal bleeding and sudden death. Surgery to repair AAA is risky, but doctor...