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There are 3739 result(s) for coronary disease mortality
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RESEARCH
How GLP-1 producing cells in the brain affect the heart and circulatory systemUniversity College London | Professor Stefan Trapp
Glucagon-like-peptide-1 (GLP-1) is a molecule made by the gut and the brain that reduces appetite and helps control blood sugar levels. Drugs that mimic the effects of GLP-1 are currently used to lower body weight and treat diabetes. Howeve...
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RESEARCH
Hunting for genes that cause bleeding disordersUniversity of Birmingham | Dr Neil Morgan
Supervised by Dr Neil Morgan, the PhD student on this project is hunting for new genes that cause bleeding disorders to work out how they cause disease. Bleeding disorders describe a group of conditions where blood does not clot properly...
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RESEARCH
Imaging methods to detect early stages of atherosclerosisSt George's, University of London | Dr Marco Massimiliano Meloni
BHF Research Fellow Dr Marco Meloni is developing better ways to image blood vessels to help doctors detect the early stages of atherosclerosis, when arteries fur up and narrow. This condition can develop over several decades without sympto...
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RESEARCH
Studying a ‘radical’ enzyme linked to high blood pressureUniversity of Glasgow | Professor Rhian Touyz
This programme of research examines how an enzyme, Nox5, contributes to high blood pressure through the production of free radicals. High free radical levels may be due to increased production or to reduced antioxidants in cells. Although ...
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RESEARCH
Creating a computer model of the heart to better understand atrial fibrillationKing's College London | Dr Steven Niederer
Normally, your heart’s natural pacemaker sends out regular electrical impulses. Atrial fibrillation (AF) is the most common heart rhythm disorder, mainly affecting people over 55. AF happens when the regular electrical impulses in the atria...
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RESEARCH
How do blood vessel cells sense and respond to blood flow?Manchester Metropolitan University | Dr Stephen White
The build-up of fatty deposits in arteries is much more likely to occur in the bends and branches of arteries, where blood flow is disrupted. Changes in flow can cause the cells that line the blood vessel wall (endothelial cells) to detach....
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RESEARCH
Understanding the biology of bleeding disordersUniversity of Birmingham | Dr Neil Morgan
Platelets are small cells that help the blood to clot after an injury and prevent excessive bleeding. Some people inherit a disorder called thrombocytopenia, where they have a low number of platelets and abnormal bleeding. Dr Morgan has...
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RESEARCH
Using injectable heart monitors to track abnormal heart rhythms in heart failure patientsUniversity of Glasgow | Professor Roy Gardner
Heart failure is a serious condition that, in 2015, affects nearly half a million people in the UK. We know that many people with heart failure experience abnormal heart rhythms – be that too fast, too slow, and/or irregular – which can be ...
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RESEARCH
Developing cell therapy to prevent heart transplant rejectionKing's College London | Professor Ajay Shah
When someone’s heart is failing, a transplant is sometimes the only treatment option. However, the new heart can be rejected by the body’s immune response, even when medicines are taken to try and prevent this. Professor Shah and his team...
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RESEARCH
Investigating the effects of new cancer treatments on the heart and the role of the BRaf proteinUniversity of Reading | Professor Angela Clerk
Cancer is a common disease and many patients are given powerful anticancer drugs in order to combat it. However, little is known about the other effects these drugs have on the body, particularly the heart and circulatory system. This labor...