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There are 3429 result(s) for coronary disease mortality
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RESEARCH
Research excellence at the University of OxfordUniversity of Oxford | Professor Hugh Watkins
In 2008 the BHF began a £34 million investment strategy to support four top UK universities as BHF Centres of Research Excellence, aiming to secure the UK’s future as a world-leading force in heart research. The University of Oxford receive...
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RESEARCH
Could SIRT6 hold the key to new drugs for atherosclerosis?University of Cambridge | Professor Martin Bennett
BHF Professor Martin Bennett and colleagues at the University of Cambridge are working out if a protein called SIRT6 could be a target for new drugs to treat atherosclerosis, a condition where fatty materials build-up inside arteries. A he...
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RESEARCH
Identifying how arteries age in humansUniversity of Cambridge | Professor Martin Bennett
BHF Professor Martin Bennett has been awarded a three-year grant to investigate how blood vessels age. As we get older our blood vessels change: cells begin to die and scar tissue accumulates in the vessel walls, making them less elastic. P...
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RESEARCH
Blood platelet size and cardiovascular eventsKing's College London | Professor Manuel Mayr
Platelets are tiny cells, which are vital for blood clotting – they stick together at the site of injury and form a plug to prevent further blood loss. However some people have larger platelets than others, which increases their risk of hav...
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RESEARCH
Understanding the early stages of how our veins and arteries stiffen with ageUniversity of East Anglia | Dr Derek Warren
As we age, our veins and arteries become less flexible, and this contributes to the development of heart and circulatory disease. The biological processes that initiate the stiffening of our blood vessels are still not well understood. By u...
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RESEARCH
How does being born prematurely increase the risk of stroke in adulthood?University of Oxford | Professor Paul Leeson
Previous studies have shown that being born prematurely can increase your risk of high blood pressure and stroke in adult life. Professor Paul Leeson and colleagues are using sophisticated imaging techniques to analyse the blood vessels in ...
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RESEARCH
Understanding the molecular changes that could lead to aortic aneurysmKing's College London | Professor Manuel Mayr
Aneurysms are balloon-like bulges that form in blood vessels, for example in the body's main artery in the chest - the aorta. Some aneurysms may stay small but others can burst and be fatal. There are currently no effective treatments for a...
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RESEARCH
When, where and what changes occur in cells in the heart during heart failure?Imperial College London | Dr Michela Noseda
Heart failure affects millions of people around the world. During heart failure, the heart is unable to pump strongly enough to meet the day-to-day demands of the body. It can also lead to electrical faults in the heart. Now, researchers in...
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RESEARCH
Investigating the role of fats in the heart in type 2 diabetesUniversity of Oxford | Dr Lisa Heather
Heart and circulatory disease is the leading cause of death in people with type 2 diabetes. In type 2 diabetes the heart is less able to pump blood around the body, and this has been linked to changes in how the heart makes its own energy f...
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RESEARCH
Why do we like salt so much, and how does it cause high blood pressure?University of Edinburgh | Professor Matthew Bailey
High blood pressure is a major risk factor for heart and circulatory disease and it affects millions of people in the UK. Having too much salt in our diet can lead to high blood pressure, so it’s important that we try to limit our int...