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Our research highlights of 2023
It has been a phenomenal year in the world of our research. From lifesaving dementia treatment to using fruit flies to better understand how the heart is formed, each discovery we fund helps take us a step closer to beating heartbreak forever. Here we take a look back at some of our research breakthroughs of 2023.
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RESEARCH
How Cezanne protects blood vesselsUniversity of Sheffield | Professor Paul Evans
Heart attacks and strokes result from the build-up of fatty plaques within blood vessels, a condition called atherosclerosis. Branches and bends of arteries that are exposed to disturbed blood flow patterns are susceptible to inflammation a...
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RESEARCH
Determining the heart safety of a new cancer drugSt George's, University of London | Dr Daniel Meijles
Research suggests that a class of cancer medicines called Raf inhibitors can affect cell-protective mechanisms in the heart. This project will determine whether these drugs could have a detrimental effect in people with heart and circulator...
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"We’re waiting too long for heart care"
BHF is calling on the UK Government to address the growing heart care crisis. Sign up to our petition now.
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Medication side effects: how to deal with them
Our Senior Cardiac Nurse shares expert tips for adjusting to new medications.
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RESEARCH
First clinical trial of gene therapy to prevent graft failure post CABGUniversity of Glasgow | Professor Andrew Howard Baker
Doctors sometimes recommend coronary bypass surgery for people with coronary heart disease (CHD), to improve the blood supply to heart muscle. It involves taking an artery or vein from elsewhere in the body and grafting it into the coronary...
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RESEARCH
Developing 3D MRI for a better image of the heart and vesselsKing's College London | Professor Sven Plein
Heart patients commonly need to undergo imaging of their heart and vessels to identify what is wrong or to understand the extent of any damage (for example, after a heart attack). The benefit of MRI compared with some other tests is that it...
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RESEARCH
Determining the importance of STAT5A in atherosclerosisUniversity of Sheffield | Professor Paul Evans
Atherosclerosis, the build-up of fatty deposits in arteries, is started by inflammation of the cells that line blood vessels. This occurs mostly in the bends and branches of arteries, where blood flow is disrupted. By contrast, straighter p...
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RESEARCH
Understanding how calcium-sensing receptors influence blood pressureSt George's, University of London | Professor Anthony Albert
Abnormal contraction of blood vessels leads to high blood pressure, which in turn is a significant risk factor for heart and circulatory diseases. Recently, a group of molecules called calcium-sensing receptors (CaSRs) have been shown to ...
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RESEARCH
Harnessing an active ingredient of fruit and vegetables to fight atherosclerosisCardiff University | Professor Dipak Ramji
Atherosclerosis is the name that doctors use for the narrowing of arteries due to fatty plaques building up in the walls of the blood vessel. It’s the condition that leads to angina, heart attacks and some strokes. The development of statin...