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Clinical Study Grants support clinical trials and observational studies of specific patient groups. Previous awards have included a broad range of types and sizes of study, e.g. single centre pilot studies, large multi-centre trials, UK arms of international trials, sub-studies of existing trials.

Lacunar stroke is a type of stroke that could be contributing to dementia. Sarah Brealey hears how Professor Joanna Wardlaw and her colleagues are tackling the problem.

RESEARCH

Imperial College London | Professor Anna Randi

The cells that make up the innermost lining of our blood vessels are called ‘endothelial cells’. They actively influence all sorts of functions including how permeable the vessels are, how they grow, and the tendency for blood to clot withi...

RESEARCH

University of Southampton | Dr Hugh Gallagher

Chronic kidney disease (CKD) is common, particularly in the elderly. In some cases, it can advance into life-threatening kidney problems. But the greatest health threat to most people with CKD is that it significantly increases their risk o...

RESEARCH

St George's, University of London | Dr Daniel Meijles

Research suggests that a class of cancer medicines called Raf inhibitors can affect cell-protective mechanisms in the heart. This project will determine whether these drugs could have a detrimental effect in people with heart and circulator...

RESEARCH

University of Nottingham | Professor Philip Bath

High blood pressure is common in people who have a stroke because of a blood clot or a bleed – called ischaemic or haemorrhagic stroke – and people are more likely to die or become disabled because of it. So far trials to lower blood pressu...

A angiogram is a common test for people with possible heart symptoms. Professor Julian Gunn explains the different types of angiogram.

What is inflammation and how can it be dangerous? Get the latest research.

It has been a phenomenal year in the world of our research. From lifesaving dementia treatment to using fruit flies to better understand how the heart is formed, each discovery we fund helps take us a step closer to beating heartbreak forever. Here we take a look back at some of our research breakthroughs of 2023.

RESEARCH

University of Sheffield | Professor Paul Evans

Heart attacks and strokes result from the build-up of fatty plaques within blood vessels, a condition called atherosclerosis. Branches and bends of arteries that are exposed to disturbed blood flow patterns are susceptible to inflammation a...