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'Good' HDL cholesterol has puzzled researchers for many years. Despite studies showing raising it reduces heart disease risk, clinical trials where HDL cholesterol was raised have shown little promise. Our researchers, working in an international collaboration with the University of Pennsylvania, have shone new light on the mystery.

Our 2024-25 Annual Report and Accounts underlines our outstanding achievements and bold new vision to secure a world in which everyone has a healthier heart for longer.

RESEARCH

University of Glasgow | Professor Andrew Howard Baker

Doctors sometimes recommend coronary bypass surgery for people with coronary heart disease (CHD), to improve the blood supply to heart muscle. It involves taking an artery or vein from elsewhere in the body and grafting it into the coronary...

New research we're funding in Wales could lead to better outcomes for patients in the future. Dr Harry Ahmed is a GP from Rhondda Cynon Taf and Senior Clinical Lecturer in Epidemiology at Cardiff University's School of Medicine. He's investigating if there’s a link between patients having urinary tract infections (UTIs) and suffering a heart attack or stroke.

RECIPE

Dessert, Serves: 4, Prep time: 15

Apple wedges baked in a cinnamon-spiced batter make this a mouth-watering and healthy dessert.

RESEARCH

University of Nottingham | Dr Kenton Arkill

Dr Kenton Arkill and his team at the University of Nottingham are developing a new tool to help researchers measure the force of blood flowing through blood vessels to better understand how blood vessels work and what goes wrong in cardiova...

RESEARCH

University of Manchester | Professor Mark R Boyett

The heartbeat begins at the natural pacemaker of the heart – called the sinoatrial node. The beat is initiated by two systems, called the ‘membrane clock’ and the ‘calcium clock’. As we get older or develop heart failure, the pacemaker no l...

Many people with heart conditions face mental health issues as a result. We hear how Margaret Brain beat hers and shows where you can find help.

RESEARCH

University College London | Professor Brian Davidson

The UK Clinical Research Collaboration, or UKCRC, brings together the NHS, research funders, industry, regulatory bodies, patient groups and universities in the UK to promote high quality clinical research that benefits patients. One of...