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RESEARCH

Searching for molecules in the blood to prevent or treat heart disease

University of Oxford | Dr Michael Holmes

Although research has revealed the main causes of heart disease, there is still much detail we don’t know. In this fellowship, Dr Holmes intends to analyse the blood in intricate detail to determine whether certain molecules and processes c...

RESEARCH

Dantrolene and VKII-86 as possible treatments for CPVT and other arrhythmias

University of Manchester | Dr Luigi Venetucci

Calcium is vital for the function of our heart and it is fundamental to the control of our heartbeat. A protein called the ryanodine receptor is crucial in the process; it allows calcium to move to areas in the heart cell where it can be us...

RESEARCH

Can telling the body to clear inflammation prevent atherosclerosis?

University of Aberdeen | Dr Dawn Thompson

The development of ‘fatty plaques’ in the blood vessels involves chronic inflammation. Some research efforts to treat plaques or prevent them growing are focusing on this inflammation. However, treatments that dampen down inflammation run ...

RESEARCH

Kickstarting the body’s repair mechanisms after a heart attack

King's College London | Professor Francesco Dazzi

When someone suffers a heart attack, some of their heart cells die and the body is unable to replace them. This can eventually lead to heart failure. Scientists have been testing whether injecting a type of stem cell - known as mesenchymal ...

RESEARCH

Testing new treatments for CPVT

University of Manchester | Dr Luigi Venetucci

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder characterised by the onset of irregular heart rhythm during exertion. This irregular heart rhythm (often a ventricular arrhythmia) can cause collapse and sud...

RESEARCH

Microbubble contrast agents for improved ultrasound imaging of blood vessels

Heriot Watt University, Edinburgh | Dr Vassilis Sboros

Heart and circulatory disease is Britain’s biggest killer. New methods are urgently needed to quickly and accurately diagnose problems with the heart and circulatory system so that they can be treated or monitored before they become more se...

RESEARCH

Hydrogen sulphide’s role in blood vessels following a heart attack

University of Nottingham | Dr Vera Ralevic

Every year thousands of people suffer a heart attack, which starves the heart of oxygen. To help preserve its function, the heart and circulatory system respond by undergoing various changes that attempt to reduce the damage. One of these i...