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RESEARCH

Using IMR to measure the effects of alteplase on heart attack outcomes

University of Glasgow | Professor Colin Berry

Professor Colin Berry’s team is investigating whether a measurement taken during percutaneous coronary intervention (PCI) - a procedure where doctors open up a blocked coronary artery with a stent - can detect which patients have had blood ...

RESEARCH

A potential new anti-oxidant approach to combating atherosclerosis

University of Reading | Professor David S Leake

Researchers will investigate a potential new way to prevent the damaging effects of LDL cholesterol in arteries. ‘Bad’ LDL cholesterol contributes to artery disease, known as atherosclerosis, which causes heart attacks. Part of the proce...

RESEARCH

Uncovering the mechanisms behind pulmonary arterial hypertension, towards a cure

University of Sheffield | Professor Allan Lawrie

Pulmonary arterial hypertension (PAH) is a rare but fatal disease. It is most common in young women, who – if untreated – have a prognosis worse than some cancers. PAH is driven by unchecked cell growth in the blood vessels in the lung. Thi...

RESEARCH

Making ‘virtual’ hearts to personalise treatment for abnormal heart rhythms.

King's College London | Dr Martin Bishop

Our bodies and hearts are all unique, and treatments and procedures that work for one person may not be right for another. Many researchers are trying to develop new ways to understand this variation between individuals to allow them to pro...

RESEARCH

Attempting to slow down or prevent the development of atherosclerosis

Imperial College London | Professor Justin C Mason

Understanding how atherosclerosis develops and progresses may reveal new ways to prevent or treat the condition in the future. Cells lining the inner wall of our blood vessels are called endothelial cells, or ‘the endothelium’, and are impo...

RESEARCH

Pilot study: supervised cardiac rehabilitation after aortic aneurysm repair

St George's, University of London | Mr. Peter Holt

Aortic aneurysms, if left untreated, can rupture, causing internal bleeding and sudden death. Many patients with heart or circulatory disease are currently offered formal cardiac rehabilitation – particularly vulnerable patients who have ha...

RESEARCH

Could heart fibroblast cells help to repair damage?

Imperial College London | Professor Prakash P Punjabi

Supervised by Prakash Punjabi, a Clinical Research Training Fellow is studying cells within the heart called fibroblasts and how they can support the growth of new heart tissue. Fibroblasts help the body to repair itself after injury. But ...

RESEARCH

Finding out if protein called Brn-3b controls aortic stiffness

University College London | Dr Vishwanie Budhram-Mahadeo

Dr Vishwanie Budhram Mahadeo from University College London is studying a protein called Brn-3b, to find out if this protein could hold the key to preventing stiffness of the heart’s major artery. The aorta is a large, elastic blood ves...

RESEARCH

Understanding how the kidney helps to regulate blood pressure

University of Cambridge | Dr Kevin O'Shaughnessy

The control of sodium and potassium salts in the body is important for regulating blood pressure. This balance is regulated in a special part of the kidneys called the distal convoluted tubule, or DCT. However, the exact mechanism used by t...