Guiding clinical anatomical and functional data acquisition for personalised computational cardiac model construction used in patient-specific therapy optimisation
Our bodies and hearts are all unique, and treatments and procedures that work for one person may not be right for another. Many researchers are trying to develop new ways to understand this variation between individuals to allow them to provide more targeted treatments – an area known as personalised medicine. For people with heart conditions, this could potentially be achieved by building and testing treatments on computer models of their heart. In particular, ‘virtual’ hearts could hold the key to personalised treatment of abnormal and dangerous heart rhythms. Such models could allow doctors to test the effects of different treatments ‘on screen’, helping them choose the type of treatment best suited to each individual person’s condition. However, accurate information about the heart and its function is needed to create a reliable model. In this project, Dr Martin Bishop and his team at King’s College London will determine the specific types and level of detail of measurements needed to build accurate models of the electrical activity of the heart. For example, they will test whether more detailed scans of the heart than are currently the clinical ‘standard’ would be required to make the models useful in clinical practice. This work has the potential to inform and guide the future construction and use of virtual hearts for personalised treatment of abnormal heart rhythms.
Project details
| Grant amount | £168,447 |
|---|---|
| Grant type | Project Grants |
| Application type | Project Grant |
| Start Date | 25 July 2019 |
| Duration | 2 years, 6 months |
| Reference | PG/18/74/34077 |
| Status | In Progress |
