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  • RESEARCH

    Building 3-D blood vessels to study blood clotting

    Keele University | Professor Ying Yang

    In this PhD studentship the researchers will grow human blood vessels in the laboratory from cells taken from human donors. They propose that the 3-D engineered blood vessels can be used to study the process of blood clotting. Platelets are...

  • RESEARCH

    How dying cells inflame fatty plaques in atherosclerosis

    University of Cambridge | Dr Murray Clarke

    Heart attacks are caused by rupture of abnormal thickenings (atherosclerotic plaques) that form within the coronary artery wall, leading to clots that block blood flow. One cause of plaque rupture is thought to be the loss of muscle cells, ...

  • Previous Clinical Study Grant Awards

    Clinical Study Grants support clinical trials and observational studies of specific patient groups. Previous awards have included a broad range of types and sizes of study, e.g. single centre pilot studies, large multi-centre trials, UK arms of international trials, sub-studies of existing trials.

  • RESEARCH

    Understanding kugeln, a new avenue of research in stroke and dementia

    University of Sheffield | Professor Tim Chico

    Sheffield researchers are investigating an intriguing phenomenon they discovered in blood vessels in the brain. Understanding how blood vessels develop in the brain may help us to find ways to tackle diseases including stroke and dementi...

  • RESEARCH

    Studying the eye to improve detection of small vessel disease in the brain

    University of Edinburgh | Professor Joanna Wardlaw

    Cerebral small vessel disease (SVD) is a common disease affecting the small blood vessels of the brain. SVD is responsible for nearly half of all dementia cases and a fifth of all strokes worldwide. The cause of the disease is poorly unders...

  • RESEARCH

    A new MRI technique detecting dangerous fatty plaques that could cause stroke

    University of Oxford | Professor Robin P Choudhury

    Dr Luca Biasiolli is developing a new imaging tool to help doctors detect plaques in the carotid artery supplying blood to the brain that are most likely to rupture, leading to a stroke. Modern imaging techniques such as magnetic resonan...

  • RESEARCH

    Could high-density lipoproteins treat abdominal aortic aneurysms?

    St George's, University of London | Professor Gillian W Cockerill

    An abdominal aortic aneurysm is where there is a weakening in the main blood vessel in the abdomen, which results in a breakdown of the vessel. Professor Gillian W Cockerill and colleagues at St George's University London have recently show...

  • RESEARCH

    Investigating a protein that promotes blood vessel repair

    King's College London | Dr Lingfang Zeng

    Dr Lingfang Zeng and his team at King’s College London study the cells that make up the inner lining of blood vessels (the endothelium).These cells, called endothelial cells, do not work correctly in several heart and circulatory diseases, ...

  • RESEARCH

    Which proteins determine the correct function of artery cells?

    University of Cambridge | Professor Christopher W J Smith

    Professor Christopher Smith and his colleagues at the University of Cambridge are studying a group of proteins that help to determine the correct function of vascular smooth muscle cells (VSMC) that line arteries. DNA is a chemical code th...