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RESEARCH
Understanding how calcium-sensing receptors influence blood pressureSt George's, University of London | Professor Anthony Albert
Abnormal contraction of blood vessels leads to high blood pressure, which in turn is a significant risk factor for heart and circulatory diseases. Recently, a group of molecules called calcium-sensing receptors (CaSRs) have been shown to ...
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RESEARCH
Uncovering the mechanisms behind pulmonary arterial hypertension, towards a cureUniversity of Sheffield | Professor Allan Lawrie
Pulmonary arterial hypertension (PAH) is a rare but fatal disease. It is most common in young women, who – if untreated – have a prognosis worse than some cancers. PAH is driven by unchecked cell growth in the blood vessels in the lung. Thi...
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RESEARCH
How does cAMP exert anti-inflammatory effects in blood vessels?University of Bristol | Dr Mark Bond
Bristol researchers are testing their theory of how blood vessel-damaging inflammation occurs in the body. Inflammation is an essential process for healthy healing after injury. However, long-term inflammation is involved in many heart a...
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RESEARCH
How blood vessel smooth muscle cells become syntheticUniversity of Warwick | Dr Anne Straube
The walls of blood vessels are lined by cells that contract or relax to control blood flow. These cells are important for repairing the vessel wall after an injury. To do this, the cells become ‘synthetic’: they produce and reorganise prote...
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RESEARCH
Understanding the mechanism of cell growth that leads to thickening of blood vesselsUniversity of Cambridge | Dr Helle F Jorgensen
Vascular smooth muscle cells (VSMCs) are part of the blood vessels wall. When they multiply more than they should, it leads to a thickening in the blood vessel . This occurs during atherosclerosis where fatty materials builds up in the lini...
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