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RESEARCH
Is QKI the missing link causing the damaging effects of diabetes on our blood vessels?Queen's University Belfast | Dr Andriana Margariti
It is estimated that by 2045 there will be 629 million people with diabetes across the globe. Diabetes is a major cause of damage to our blood vessels, which can lead to heart attacks, stroke, kidney failure and blindness. The reason diabet...
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RESEARCH
How does cAMP exert anti-inflammatory effects in blood vessels?University of Bristol | Dr Mark Bond
Bristol researchers are testing their theory of how blood vessel-damaging inflammation occurs in the body. Inflammation is an essential process for healthy healing after injury. However, long-term inflammation is involved in many heart a...
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RESEARCH
Unravelling the effects of genetic variation in pulmonary hypertensionImperial College London | Dr Christopher Rhodes
Over 9000 European people with rare diseases had their genomes sequenced as part of the UK’s BRIDGE project. One of diseases studied was pulmonary arterial hypertension (PAH) – high blood pressure in the lungs, which leads to heart failure....
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RESEARCH
How Cezanne protects blood vesselsUniversity of Sheffield | Professor Paul Evans
Heart attacks and strokes result from the build-up of fatty plaques within blood vessels, a condition called atherosclerosis. Branches and bends of arteries that are exposed to disturbed blood flow patterns are susceptible to inflammation a...
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RESEARCH
What controls the production of new platelets involved in blood clotting?University of Cambridge | Dr Marloes Tijssen
Coronary heart disease is the UK’s single biggest killer. One of the main contributors is thrombosis – a serious condition that can develop when a blood vessel becomes damaged and small blood cells called platelets stick to the damaged area...
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RESEARCH
Keeping track of young plateletsUniversity of Birmingham | Dr Paul Harrison
Platelets, the tiny cells in our body that help the blood to clot, live for only ten days. Because of this short lifespan, conditions that cause low platelet counts, such as thrombocytopenia, are usually caused by problems in producing enou...
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RESEARCH
Understanding who might have side-effects when taking statinsUniversity of Oxford | Dr James Sheppard
Statins are cholesterol-lowering drugs that prevent heart attack and stroke. However, some people may experience side effects when taking them such as muscle pain, liver injury and diabetes, which can stop some people from taking them. This...
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RESEARCH
Testing a simple way to get more teenagers activeSwansea University | Professor Sinead Brophy
Professor Sinead Brophy and her colleagues at the University of Swansea, in partnership with a local council, are finding out if a simple activity voucher system could help teenagers get active and improve their heart health. Regular exe...
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Fear of causing harm would prevent couples from giving lifesaving CPR
Around half of people who live with their partner said the fear of causing harm would make them reluctant to give CPR if someone had a cardiac arrest in front of them, according to new data we've released by to mark Heart Month.
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RESEARCH
Studying the nanomechanics of hypertrophic cardiomyopathyQueen Mary, University of London | Dr Arianna Fornili
Hypertrophic cardiomyopathy is a common disease of the heart muscle and detailed knowledge of the mechanism of heart contraction is central to design new therapies. Contractions arise from the molecular motions of a motor protein, myosin II...