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  • RESEARCH

    How are immune cells involved in plaque development?

    University of Cambridge | Dr Andrew Sage

    BHF Intermediate Basic Science Research Fellow Dr Andrew Sage is studying how different parts of our immune system play a role in boosting or reducing plaque development in atherosclerosis. As atherosclerosis happens, blood vessels become ‘...

  • RESEARCH

    Finding new ways to stop blood from clotting without increasing the risk of bleeding

    University of Leeds | Professor Helen Philippou

    Dr Helen Philippou and her team at the University of Leeds are looking for new ways to protect people who are diagnosed with heart and circulatory disease from developing further blood clots. Currently they receive an anti-platelet drug and...

  • What is a CT scan of the brain?

    A CT scan can be used to diagnose a stroke and other brain problems, as Professor Joanna Wardlaw explains to Senior Cardiac Nurse Emily McGrath.

  • RESEARCH

    Pinpointing the proteins that promote atherosclerosis

    Lancaster University | Professor David Middleton

    Deposits of amyloid protein are probably better known for being involved in neurodegenerative disorders such as Alzheimer’s disease. But there is increasing evidence that these amyloid ‘plaques’ also accumulate with the fatty deposits that ...

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  • RESEARCH

    Targeting mast cells to prevent deep vein thrombosis

    University of Birmingham | Dr Alexander Brill

    Deep vein thrombosis (DVT) is a blood clot that develops within a deep vein in the body, usually in the leg. Large cells found close to blood vessels called mast cells (MCs) are known to be important in DVT, but it is not known what trigger...

  • RESEARCH

    How RhoJ helps new blood vessels to grow

    University of Birmingham | Dr Victoria Heath

    Dr Victoria Heath and her team at the University of Birmingham are studying the processes that control angiogenesis - when blood vessels form from existing vessels. This process is important in health and in heart and circulatory disease. ...

  • RESEARCH

    Pulmonary hypertension - exploring a potential new treatment

    University of Manchester | Professor Alison Gurney

    Pulmonary arterial hypertension (PAH) occurs when abnormally high blood pressure in the arteries carrying blood to the lungs causes damage to the right side of the heart. Symptoms include breathlessness or tiredness. The condition can lead ...

  • RESEARCH

    Developing a new algorithm to detect arrhythmias and prevent sudden cardiac death

    Imperial College London | Dr Zachary Whinnett

    An arrhythmia is an abnormal heart rhythm. Implantable cardioverter defibrillators (ICDs) are small devices placed within the body that prevent sudden cardiac death by treating life-threatening ‘ventricular’ arrhythmias. If an ICD detects a...

  • RESEARCH

    How is oestrogen linked to pulmonary arterial hypertension?

    University of Strathclyde | Professor Margaret MacLean

    Professor Margaret MacLean and colleagues at the University of Glasgow are studying why more women than men develop pulmonary arterial hypertension (PAH), but men die more quickly. In PAH, the pulmonary arteries (arteries of the lungs) ...