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There are 3739 result(s) for coronary disease mortality
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RESEARCH
Can KCNE1 influence the heart’s electrical activity in long-QT syndrome?University of Bristol | Professor Jules Hancox
Professor Jules Hancox and colleagues at the University of Bristol will investigate how a small protein called KCNE1 can influence the electrical activity of the heart. The KCNE1 protein interacts with potassium ion channels called hERGs wh...
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RESEARCH
How aldosterone-producing adrenal adenomas cause high blood pressureUniversity of Cambridge | Professor Morris Brown
One cause of high blood pressure is a benign tumour in the adrenal gland which secretes aldosterone, the hormone regulating salt and water balance. The over- secreting tumour is called an aldosterone-producing adrenal adenoma (APA). To unde...
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RESEARCH
Can allopurinol help people with high blood pressure and left ventricular hypertrophy?University of Dundee | Professor Jacob George
A team from the University of Dundee will conduct a clinical trial in patients with high blood pressure, looking particularly at thickening of the heart muscle (left ventricular hypertrophy). Although high blood pressure can be controlled w...
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RESEARCH
Working out how blood flow disturbances predispose to atherosclerosisUniversity of Sheffield | Dr Heather Wilson
Heart attacks and strokes result from the build-up of fatty plaques within blood vessels, called atherosclerosis. There are specific regions of arteries, such as branch points and curves, that more likely to develop fatty plaques. This is b...
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RESEARCH
How our fight-flight response affects blood vesselsKing's College London | Professor Philip Chowienczyk
Acute psychological stress is thought to be able to precipitate a cardiovascular event, like a heart attack. The release of nitric oxide, a molecule of key importance in cardiovascular health is strongly influenced by stress and may protect...
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RESEARCH
Studying problems with calcium channels in the heartCardiff University | Dr Nia Thomas
Coordinated contraction of the heart muscle during each heartbeat is only achieved when calcium movement in heart cells is well controlled. Unfortunately, we now know that genetic errors in key molecules and structures of the heart that con...
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RESEARCH
Studying a protein’s role in causing congenital heart defectsUniversity College London | Professor Peter Scambler
Professor Scambler and his team study how the heart develops in the embryo by investigating the genes involved in normal development. They are particularly interested in what goes wrong in the developing heart to cause congenital heart dise...
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RESEARCH
Can tranexamic acid prevent or slow bleeding in the brain?University of Nottingham | Dr Robert Dineen
Bleeding into the brain can lead to stroke, and subsequent bleeds that continue afterwards put the patient at higher risk of death or disability. Tranexamic acid is a drug that is currently used against bleeding in acute trauma, and it also...
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RESEARCH
How tissue factor triggers blood clottingCardiff University | Professor Peter Collins
When blood clots form in blood vessels they block the flow of blood and can cause heart attacks and strokes. Finding new ways to manage blood clotting could prevent and treat blood clots that lead to a heart attack or stroke. Blood clot...
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RESEARCH
New tools to help stem cells repair damaged heartsUniversity College London | Dr Daniel Stuckey
BHF Intermediate Basic Science Research Fellow Dr Daniel Stuckey is developing new tools to give stem cells the best chance of repairing damaged heart tissue. After a heart attack, heart muscle tissue becomes damaged and has a limited a...