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RESEARCH

Understanding how integrin proteins regulate cells that line the blood vessels

University of Cambridge | Professor Richard Farndale

Supervised by Professor Richard Farndale, the PhD student is investigating the behaviour of endothelial cells that line the inside of a blood vessel. These cells control how leaky a blood vessel is, preventing blood loss but allowing nutrie...

RESEARCH

Equipping scientists with state-of-the-art technology for analysis of small molecules in heart and circulatory diseases

Cardiff University | Professor Valerie O'Donnell

It is essential for scientists studying heart and circulatory diseases to be able to quickly and comprehensively analyse all the different types of fats (known as lipids) in a sample of blood or tissue. The most effective technology for doi...

RESEARCH

Understanding how pericytes drive new blood vessel growth

University of Bristol | Professor Paolo Madeddu

Pericytes are cells that surround blood vessels and play an important role in the growth of new blood vessels (known as angiogenesis). When there is a reduction in blood supply (ischemia), the growth of new blood vessels limits the damage c...

RESEARCH

Does a protein called Syk offer hope for new anti-clotting drugs?

University of Birmingham | Professor Stephen P Watson

Supervised by BHF Professor Stephen Watson, a PhD student is working to understand if a protein called Syk could help to prevent blood clotting. Platelets are small cells in the blood which clump together at sites of injury to prevent bloo...

RESEARCH

Using computer algorithms to look for heart attack and stroke risk factors in blood samples

University of Cambridge | Dr William Astle

Atherosclerosis is the disease process in which plaques containing fat and white blood cells build up in the walls of arteries. These can rupture, activating tiny blood cells called platelets to clump together and form a clot. Heart attacks...

RESEARCH

Understanding how to keep the blood vessel barrier intact

University of Edinburgh | Dr Sonja Vermeren (nee Krugmann)

The cells that line our blood vessels (called endothelial cells) form an important barrier that contains blood inside the vessels and controls the entry of substances from the blood into surrounding tissues. Inflammation of the blood vessel...

Saturated fats and your heart explained

Our Senior Dietitian gives you the full story.