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There are 3447 result(s) for coronary disease mortality
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RESEARCH
Studying a heart protein that senses blood flow and mechanical stressUniversity of Leeds | Dr Sarah C Calaghan
Supervised by Dr Jing Li, this PhD student is working out how heart muscle cells respond to mechanical stress. Heart muscle is made up of cells that are constantly exposed to mechanical stimulation as the heart beats and blood flows thro...
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RESEARCH
How drugs can cause life threatening heart rhythm disturbancesUniversity of Bristol | Dr Christopher Dempsey
For the heart to pump blood around the body efficiently, electrical signals must travel through the chambers of the heart in an organised and rhythmic way. These signals are co-ordinated by proteins in heart cells called ion channels. A div...
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RESEARCH
How is Bam32 regulated in platelets and does it contribute to platelet function and thrombosis?University of Bristol | Professor Ingeborg Hers
Thrombosis is a serious condition that can develop when a blood vessel becomes damaged and small blood cells called platelets stick to the damaged area, forming a clot. If the clot breaks away from the vessel wall, it can block an artery le...
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RESEARCH
The role of the KCNJ5 potassium channel in blood pressure controlUniversity of Cambridge | Dr Kevin O'Shaughnessy
Up to 10% of people with high blood pressure (hypertension) have an excess of a hormone called aldosterone. Aldosterone is secreted by the adrenal gland and conserves salt in the body, thereby controlling blood pressure. In some people with...
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RESEARCH
Identifying how beta-blockers might prevent heart muscle damage from pulmonary hypertensionUniversity of Leeds | Professor Edward White
Pulmonary hypertension is a serious condition that affects blood vessels in the lung and can lead to heart failure affecting the right side of the heart. Medicines called beta-blockers reduce the effect of chemicals such as adrenaline on th...
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RESEARCH
How cardiac hypertrophy leads to heart rhythm disturbancesUniversity of Surrey | Dr Rita Jabr
Dr Rita Jabr and Professor Christopher Fry from the University of Surrey will be investigating the potentially dangerous disturbances to heart rhythm that can occur as a result of cardiac hypertrophy. Cardiac hypertrophy is enlargement of t...
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RESEARCH
Preventing blood clots by stopping P2X1 receptor activation on plateletsUniversity of Cambridge | Dr Andrew Thompson
Heart attacks and strokes are caused by blood clots (thrombosis) that prevent blood from reaching the heart and brain. There are drugs available that prevent these clots from forming but they can cause unwanted bleeding. New drugs to preven...
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RESEARCH
Alternative ways to treat pulmonary hypertensionImperial College London | Professor Ian Adcock
Pulmonary arterial hypertension (PAH) is abnormally high blood pressure in the arteries carrying blood to the lungs, causing damage to the right side of the heart. Symptoms include breathlessness or tiredness. The condition can lead to deat...
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RESEARCH
Obesity in pregnancy: can a drug for diabetes prevent high blood pressure from developing?University of Cambridge | Professor Susan E Ozanne
We know that maintaining a healthy weight increases the chances of a healthy pregnancy. Obesity in pregnancy has become much more common in recent years and can have long-term health consequences for both mothers and babies. For babies, the...
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RESEARCH
How volume receptors in the heart affect blood pressureDurham University | Dr Susan Pyner
High blood pressure (hypertension) can increase the risk of a heart attack, stroke or kidney disease. The brain helps to regulate blood pressure, and it does so in response to nerve signals coming from the heart that are controlled by blood...