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There are 3447 result(s) for coronary disease mortality
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RESEARCH
Targeting ZONAB to better understand inflammation and blood vessel formationUniversity College London | Professor Dr Maria Balda
The insides of blood vessels are made up of a thin sheet of cells, called endothelial cells, which form a barrier between the passing blood and the vessel wall. Endothelial cells have many functions, from responding to stimuli within the bl...
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RESEARCH
Developing a new ‘virtual platelet’ to study blood clottingUniversity of Reading | Professor Jonathan Gibbins
Professor Jonathan Gibbins and his colleagues at the University of Reading are using a virtual model of a platelet to study blood clotting and look for new anti-clotting medicines to prevent people from having a heart attack or stroke. Pla...
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RESEARCH
What tips the balance to cause inflammation in atrial fibrillation?St George's, University of London | Dr Ingrid Dumitriu
Atrial fibrillation (AF) is the most common form of irregular heart rhythm, affecting more than a million people in the UK. AF interferes with the pumping action of the heart in a way that makes blood clots more likely to form, which can ca...
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RESEARCH
Working out how the ERG protein keeps blood vessels healthyImperial College London | Professor Anna Randi
ERG is a protein that controls how several genes are expressed within the endothelial cells that line the inside of blood vessels, enabling them to survive and function properly. Professor Anna Randi at Imperial College London is studying E...
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RESEARCH
Understanding kugeln, a new avenue of research in stroke and dementiaUniversity of Sheffield | Professor Tim Chico
Sheffield researchers are investigating an intriguing phenomenon they discovered in blood vessels in the brain. Understanding how blood vessels develop in the brain may help us to find ways to tackle diseases including stroke and dementi...
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RESEARCH
Testing potential drugs to halt heart scarringQueen Mary, University of London | Professor Philip Eaton
The build-up of scar tissue in the heart in response to injury such as a heart attack - a process called fibrosis - is a contributing factor to heart failure. During this process, some heart muscle cells change their identity and become fi...
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RESEARCH
Developing a realistic computer model of abnormal heart rhythmsImperial College London | Dr Emmanuel Dupont
Dr Emmanuel Dupont and his team at Imperial College London are testing a new computer simulation, which would allow researchers to study abnormal heart rhythms. To beat regularly, the heart contracts in response to complex electrical ci...
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RESEARCH
New ways to keep blood vessels openUniversity of Edinburgh | Professor Andrew Howard Baker
Patients with heart disease have damaged blood vessels, which may eventually lead to the vessels becoming blocked. This can become apparent for the patient through symptoms such as chest pain. Patients can undergo surgery to bypass or r...
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RESEARCH
Do anti-epileptic drugs prevent sudden cardiac death in people with CPVT?University of Oxford | Dr Charalampos Sigalas
CPVT1 is a rare inherited disease that affects children and young adults. It causes disturbances to the heart rhythm (arrhythmias) and can lead to sudden cardiac death. CPVT1 is caused by a genetic mutation of a protein called ryanodine re...
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RESEARCH
How do endothelial cells respond to forces from blood flow at the molecular level?University of Oxford | Dr Ellie Tzima
Endothelial cells line the inside surface of blood vessels. They are constantly exposed to shear stress – the friction generated by blood flowing across the surface of the cells. Endothelial cells respond to changes in shear stress and t...