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There are 3741 result(s) for coronary disease mortality
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RESEARCH
Studying the release of von Willebrand factor as a target for future medicinesQueen Mary, University of London | Dr Thomas Nightingale
A BHF-funded team based in London are studying how to prevent harmful blood clotting without preventing helpful clots. The body’s response to injury needs to be rapid to prevent blood loss and minimise the chance of infection. Cells that l...
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RESEARCH
Studying the causes of heart muscle fibrillationImperial College London | Professor Nicholas Peters
Professor Nicholas Peters and colleagues at Imperial College London are studying fibrillation, a heart rhythm disorder where electrical current flows through the heart muscle in an uncoordinated and irregular way. He wants to identify the p...
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RESEARCH
Targeting RNAs to prevent heart attacksUniversity of Edinburgh | Professor Andrew Howard Baker
When protein molecules are produced from genes contained within DNA, there is an intermediate molecule called RNA that, until recently, was thought to simply be there to produce the protein. Now, scientists know that there are hundreds of t...
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RESEARCH
Developing urgently needed treatments for aortic aneurysmsUniversity of Leeds | Dr Marc Bailey
An abdominal aortic aneurysm (AAA) is a ballooning of the main blood vessel in the abdomen. Once an aneurysm develops it tends to grow over time with no symptoms, and if it bursts, it is usually fatal. The only treatment is surgery, but thi...
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RESEARCH
Working out how arteries sense blood flowUniversity of Leeds | Dr Jian Shi
Dr Jian Shi from the University of Leeds is studying how arteries ‘sense’ blood flow. Blood flow has a major effect on artery health – arteries are more likely to become diseased in areas where the flow is disturbed, leading to heart attack...
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RESEARCH
An important new role for actin in atherosclerosisUniversity of Bristol | Dr Mark Bond
Atherosclerosis is the process in arteries that causes them to become narrowed or blocked, and can cause a stroke or heart attack. During atherosclerosis, the growth and movement of cells in the walls of blood vessels becomes uncontrolled, ...
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RESEARCH
Could an anti-diabetic drug be used to battle heart diseases?University of Dundee | Dr Graham Rena
Inflammation is an important way of our bodies protecting us from infection and ill health. But, when inflammation is sustained and badly controlled, it can damage the cells in our heart and blood vessels and be responsible for the developm...
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RESEARCH
Developing ways to personalise digoxin treatmentUniversity of Birmingham | Dr Davor Pavlovic
Digoxin is a common treatment for people with atrial fibrillation and heart failure, but it doesn’t always work as well as expected. Dr Pavlovic’s team at the University of Birmingham has previously shown that substances in the blood called...
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RESEARCH
Safe guarding the cell’s energy sources to protect the heart during a heart attackUniversity College London | Professor Derek Hausenloy
Ischaemic heart disease commonly presents as a heart attack due to a blockage in one of the main heart arteries, depriving the heart muscle of oxygen and nutrients resulting in heart muscle injury. New treatments are required to protect the...
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RESEARCH
Understanding how the enzyme NOX4 protects against heart failureKing's College London | Professor Ajay Shah
Researchers at the King’s College London BHF Centre of Research Excellence, led by BHF Professor Ajay Shah have been studying enzymes called NADPH oxidases (NOXs). These enzymes make chemicals – called free radicals – which are considered b...