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There are 3435 result(s) for coronary disease mortality
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RESEARCH
Studying the role of microRNAs in hypertrophic cardiomyopathyKing's College London | Dr Seda Eminaga
A common cause of sudden cardiac arrest in young people is hypertrophic cardiomyopathy (HCM). HCM occurs when cells in the heart muscle increase in size. Eventually they can cause the walls of the two cavities in the heart – known as the ve...
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RESEARCH
An important new role for actin in atherosclerosisUniversity of Bristol | Dr Mark Bond
Atherosclerosis is the process in arteries that causes them to become narrowed or blocked, and can cause a stroke or heart attack. During atherosclerosis, the growth and movement of cells in the walls of blood vessels becomes uncontrolled, ...
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RESEARCH
Finding drugs that can correct abnormal fat metabolismUniversity of East Anglia | Dr Samuel Fountain
Around 25% of our body is made up of fat. Fat cells, or adipocytes, store excess fats and sugar and release them when needed. When adipocytes stop working correctly, fat accumulated in other organs, increasing the risk of heart and circulat...
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RESEARCH
Decoding the messages sent between cells in our circulationImperial College London | Professor Justin C Mason
To maintain a healthy circulation the cells lining our arteries and veins send and receive chemical messages to and from other cells. This cell-cell communication occurs in several different ways. One way is via microscopic particles releas...
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RESEARCH
Engineering a new window on artery healthImperial College London | Professor Mengxing Tang
As blood flows through our arteries it exerts forces on the artery wall. The strength of these forces varies according to the shape of the vessel – whether it is straight or has bends or branches. We know that these forces affect how the ar...
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RESEARCH
How RhoJ helps new blood vessels to growUniversity of Birmingham | Dr Victoria Heath
Dr Victoria Heath and her team at the University of Birmingham are studying the processes that control angiogenesis - when blood vessels form from existing vessels. This process is important in health and in heart and circulatory disease. ...
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RESEARCH
Could bone-marrow transplantation offer a new treatment for pulmonary arterial hypertension?University of Cambridge | Professor Nicholas Morrell
Pulmonary arterial hypertension– high blood pressure in the arteries of the lungs, is a debilitating condition. New methods to prevent and treat this condition are urgently needed. Understanding the genetic and molecular causes is central t...
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RESEARCH
Can phospholipids in platelets explain bleeding or clotting diseases?Cardiff University | Professor Peter Collins
Supervised by Professor Peter Collins, the Clinical Research Training Fellow on this grant is studying how fatty ‘phospholipid’ molecules affect blood clotting. The blood clotting process, called coagulation, takes place on the surface ...
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RESEARCH
Which immune cells cause blood vessel inflammation in atherosclerosis?University of Cambridge | Professor Ziad Mallat
BHF Professor Ziad Mallat is studying how blood vessels become inflamed in atherosclerosis to see if there is a way of preventing inflammation. Atherosclerosis is caused by the build-up of fatty plaques in the walls of our arteries, and ...
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RESEARCH
How proteins cluster to ensure a regular heartbeatUniversity of Cambridge | Dr Antony Jackson
On the surface of each heart muscle cell are tiny pores, or ion channels. These open and close to let sodium, calcium and potassium ions flow in and out of the cells, and generate the electrical signal that causes the heart to contract and ...