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There are 3429 result(s) for coronary disease mortality
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RESEARCH
Von Willebrand factor: structure, activity and actionImperial College London | Dr Thomas McKinnon
Von Willebrand factor (VWF) is a large and complicated blood protein that is necessary for normal blood clotting. Low levels of VWF result in a tendency to excessive bleeding and high levels are associated with thrombosis (when a blood clot...
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RESEARCH
Developing a potential gene therapy to prevent heart failure after heart attackUniversity of Glasgow | Professor Stuart A Nicklin
During a heart attack, part of the heart muscle is starved of its oxygen supply. This can permanently injure the oxygen-starved area which, over time, may lead to heart failure. Current treatments to preserve the heart muscle after heart at...
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RESEARCH
Is a tiny molecule a big culprit in atrial fibrillation?University of Oxford | Dr Svetlana Reilly
BHF Intermediate Basic Science Research Fellow Dr Svetlana Reilly is studying how a small molecule called microRNA 31 (miR31) causes heart muscle changes in atrial fibrillation. Arrhythmias occur when the heart’s normal rhythm becomes d...
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RESEARCH
Accelerator award at the University of BirminghamUniversity of Birmingham | Professor Stephen P Watson
BHF-funded research is behind many of the advances that are helping people with heart and circulatory diseases to live longer, better lives. By investing in research we are supporting scientists to make potentially life-saving discoveries, ...
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RESEARCH
Studying the proteins that control heart rhythmUniversity of Oxford | Professor Ming Lei
Tiny pores, or ion channels on the surface of heart muscle cells open and close to let electrically charged sodium, calcium and potassium ions flow into and out of heart cells and generate the electrical signal that spreads from the top of ...
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RESEARCH
Identifying new targets for the prevention and treatment of atherosclerosisUniversity of Sheffield | Professor Paul Evans
Patients with atherosclerosis have damaged arteries, caused by a gradual build-up of fat within the artery wall. The body’s immune cells invade the artery wall to remove the fat but can get trapped there, forming a plaque. Plaque is made up...
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RESEARCH
Can statins decrease the risk of atrial fibrillation after heart surgery?University of Oxford | Professor Barbara Casadei
BHF Professor Casadei, at the University of Oxford, is researching the causes of the abnormal heart rhythm, atrial fibrillation (AF), and has identified an important protective role for a gas called nitric oxide (NO). Professor Casadei has...
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RESEARCH
How do genetic faults cause inherited heart muscle diseases?Imperial College London | Professor Steven B Marston
Diseases of the heart muscle are called cardiomyopathies and can cause heart failure and sudden death, even in young people. Two of these conditions – hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) – are caused by faults...
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RESEARCH
The role of the brain peptide adrenomedullin in hypertensionUniversity of Bristol | Professor David Murphy
High blood pressure (hypertension) affects around one in three adults in England and Scotland and significantly increases a person’s risk of developing heart disease, heart failure and stroke. Scientists have struggled to pinpoint the exact...
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RESEARCH
Research excellence at the University of EdinburghUniversity of Edinburgh | Professor John J Mullins
In 2008 the BHF began a £34 million investment strategy to support four top UK universities as BHF Centres of Research Excellence, aiming to secure the UK’s future as a world-leading force in heart research. One of these institutions was th...