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There are 3739 result(s) for coronary disease mortality
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RESEARCH
Following the TRAIL to pulmonary arterial hypertensionUniversity of Sheffield | Professor Allan Lawrie
In this Senior Fellowship, Dr Lawrie, based at the University of Sheffield, will investigate the role of two proteins TRAIL and OPG in pulmonary arterial hypertension (PAH), a rare but devastating condition where high blood pressure in the ...
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RESEARCH
How Cezanne protects blood vesselsUniversity of Sheffield | Professor Paul Evans
Heart attacks and strokes result from the build-up of fatty plaques within blood vessels, a condition called atherosclerosis. Branches and bends of arteries that are exposed to disturbed blood flow patterns are susceptible to inflammation a...
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RESEARCH
Is the positioning of proteins on the surface of heart cells important for atrial fibrillation?Imperial College London | Professor Julia Gorelik
Atrial fibrillation (AF) is the most common form of irregular heart rhythm, when the normal synchronised contraction of the upper chambers (atria) of the heart goes awry. This can have life-threatening consequences because it increases the ...
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RESEARCH
Investigating a new candidate cell for growth and repair of blood vesselsUniversity College London | Professor Christiana Ruhrberg
Damage or disease in our blood vessels can lead to heart attacks, strokes or problems with the limbs or vision. Stem cell research – part of a field known as ‘regenerative medicine’ - offers hope for a new approach to treating these conditi...
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RESEARCH
Could empagliflozin be used to treat both diabetes and heart failure?University of Dundee | Professor Chim Lang
Professor Chim Lang and colleagues at the University of Dundee are looking at whether a drug called empagliflozin could treat people with both diabetes and heart failure. People with diabetes are at greater risk of developing coronary arte...
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RESEARCH
Understanding the biology underlying broken heart syndromeImperial College London | Professor Sian Harding
Supervised by Professor Sian Harding, this MBPhD student is working out what causes stress cardiomyopathy, or broken heart syndrome (Takotsubo syndrome). In broken heart syndrome, excess adrenaline after stressful events like bereavemen...
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RESEARCH
Developing 3D MRI for a better image of the heart and vesselsKing's College London | Professor Sven Plein
Heart patients commonly need to undergo imaging of their heart and vessels to identify what is wrong or to understand the extent of any damage (for example, after a heart attack). The benefit of MRI compared with some other tests is that it...
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RESEARCH
Understanding how integrin proteins regulate cells that line the blood vesselsUniversity of Cambridge | Professor Richard Farndale
Supervised by Professor Richard Farndale, the PhD student is investigating the behaviour of endothelial cells that line the inside of a blood vessel. These cells control how leaky a blood vessel is, preventing blood loss but allowing nutrie...
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RESEARCH
Do certain kinds of mechanical stress increase chances of atherosclerosis development?Imperial College London | Professor Peter Weinberg
In atherosclerosis, some parts of a single blood vessel appear to be more at risk of developing areas of fatty plaques – which can eventually rupture to cause a heart attack – than others. Professor Peter Weinberg and his team have been awa...
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RESEARCH
Finding preventable causes of heart and circulatory diseasesUniversity of Cambridge | Professor John Danesh
Understanding the direct causes of heart and circulatory diseases would help to prevent more people dying from them. However, it can be difficult to distinguish whether something causes a particular disease, or happens to be more common in ...