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  • RESEARCH

    A clinical trial to improve the treatment of people who have a stroke in their sleep

    University of Leicester | Professor Thompson Robinson

    Most strokes are caused by a blood clot in an artery that feeds the brain – called ischaemic stroke. People who have an ischaemic stroke will usually be given clot-busting medicine to restore blood flow to the brain. If this is done within...

  • RESEARCH

    Can tranexamic acid prevent or slow bleeding in the brain?

    University of Nottingham | Dr Robert Dineen

    Bleeding into the brain can lead to stroke, and subsequent bleeds that continue afterwards put the patient at higher risk of death or disability. Tranexamic acid is a drug that is currently used against bleeding in acute trauma, and it also...

  • RESEARCH

    Modelling blood flow before and after vascular surgery

    University College London | Dr Vanessa Diaz

    Circulatory diseases are complicated to treat and can vary between individuals. When choosing from different treatment options available, doctors gather information about the shape of affected blood vessels using scans. But these often cann...

  • RESEARCH

    Revealing the role of two proteins in congenital defects of the circulation

    University College London | Dr Paul Frankel

    The circulation system develops in the unborn baby in the earliest weeks and months of life. The human body has three main types of vessels: arteries that transport oxygenated blood from the heart to the organs, veins to carry poorly-oxygen...

  • RESEARCH

    Hunting for new genes that cause aneurysms

    St George's, University of London | Professor Elijah Behr

    A thoracic aortic aneurysm is a widening or bulging of the aorta in your chest – the aorta is the largest blood vessel in the body, responsible for carrying blood out of your heart. If the aneurysm bursts, it can be fatal. In recent years, ...

  • RESEARCH

    Understanding how zinc controls blood clotting

    Anglia Ruskin University | Dr Nicholas Pugh

    Blood clots form when small cells in the blood called platelets are activated and stick together. Controlling when platelets become activated is essential to ensure clotting happens when it is needed - for example, after injury - whilst lim...

  • RESEARCH

    How the activated protein C pathway prevents blood clotting

    Imperial College London | Dr Josefin Ahnstrom

    Blood clotting is regulated by several different pathways, including a pathway that involves a protein called activated protein C, which prevents clotting. To work properly protein C relies on a partner, protein S. People who lack or have a...

  • RESEARCH

    Switching on the brain’s defence mechanisms in stroke

    King's College London | Professor Giovanni Mann

    Many types of antioxidants have been explored in the lab as potential stroke medicines, only to then fail when tested in clinical trials. Research has therefore shifted to focus on the cell’s own antioxidant defence mechanisms. Professor M...