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RESEARCH
How does the nano-location of molecules in cells impact the heartbeat in heart failure?Imperial College London | Professor Julia Gorelik
Our heartbeat is under the control of molecular signalling systems in each heart muscle cell. In diseases including heart failure these systems can break down, sending the heartbeat into irregular and sometimes fatal patterns. Researchers a...
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RESEARCH
Revealing the genetic faults responsible for the most common aortic valve defectNewcastle University | Professor Deborah Henderson
At the entrance and exit of each of the four chambers of the heart are valves, which open and close quickly between heartbeats to stop blood flowing backwards. If the heart valves are faulty – if they don’t open properly or are leaky - they...
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RESEARCH
The effect of ‘BRaf inhibitor’ cancer drugs on the heartUniversity of Reading | Professor Angela Clerk
It is well known that medicines prescribed to treat one condition can have side effects on other parts of the body. New drugs that are being used to treat some types of cancer may have toxic effects on the heart, but not enough is yet known...
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RESEARCH
Is zinc important in ensuring the normal heartbeat?University of St Andrews | Dr Samantha Pitt
In healthy people, calcium is released from large stores in heart cells through specialised ‘gates’ called ryanodine receptors. The release of calcium into the cell causes the heart to beat strongly. But in patients with heart failure, calc...