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  • RESEARCH

    Does Piezo1 help the heart sense mechanical stress?

    University of Leeds | Dr Neil Turner

    Supervised by Dr Neil Turner, this PhD student is studying how a protein called Piezo1 helps the heart respond to mechanical stress, caused by increased force of contractions of heart muscle. Cardiac fibroblasts are cells that produce ‘s...

  • RESEARCH

    Understanding how mast cells drive inflammation in blood vessels

    Queen Mary, University of London | Professor Sussan Nourshargh

    Inflammation is an essential part of the body’s defence system against viruses and bacteria. It is also an underlying cause of many heart and circulatory conditions like atherosclerosis. Atherosclerosis is the build-up of fatty substances i...

  • RESEARCH

    Working out the cause of abnormal heart rhythms in Rett syndrome

    University of Bristol | Professor Jules Hancox

    Professor Jules Hancox and his colleagues at the University of Bristol are studying the causes of abnormal heart rhythms in Rett Syndrome, a condition caused by faults in a gene called MECP2. In Rett Syndrome, children initially thrive, but...

  • RESEARCH

    Identifying proteins that stick platelets and immune cells together

    University of Birmingham | Dr Yi Sun

    Dr Yi Sun and his colleagues at the University of Birmingham are studying platelets - small blood cells that are crucial for blood clots to form. Platelets are also involved in the development of many inflammatory diseases, including athero...

  • RESEARCH

    Developing SABRE magnetic resonance imaging techniques for heart disease

    University of Leeds | Professor Sven Plein

    The BHF, in collaboration with the Medical Research Council (as part of its Clinical Research Capabilities and Technologies Initiative) has awarded a grant to a team at the Universities of Leeds and York, led by magnetic resonance imaging (...

  • RESEARCH

    Von Willebrand factor and it role in blood clotting

    Imperial College London | Professor David A Lane

    Von Willebrand Factor (VWF) is a large blood protein. It helps cells in the blood called platelets recognise blood vessel wall damage, and makes them cluster at the sites of injury. An enzyme called ADAMTS13 controls the activity of VWF. If...

  • RESEARCH

    The role of the KCNJ5 potassium channel in blood pressure control

    University of Cambridge | Dr Kevin O'Shaughnessy

    Up to 10% of people with high blood pressure (hypertension) have an excess of a hormone called aldosterone. Aldosterone is secreted by the adrenal gland and conserves salt in the body, thereby controlling blood pressure. In some people with...

  • RESEARCH

    Trichoplein and blood vessel health in diabetes

    University of Edinburgh | Dr Andrea Caporali

    The blood vessels in the human body are lined with a thin layer of endothelial cells. In healthy people, endothelial cells help to form new vessels by migrating and dividing. In diabetic patients, these endothelial cells are faulty and weak...

  • Resistance band exercises you can do at home in 10 minutes

    Try cardiac rehab expert Hara Markos' top resistance band exercises, including pull-aparts, leg presses and bicep curls, to improve your strength and flexibility.

  • RESEARCH

    The role of cell death in heart failure

    King's College London | Professor Kinya Otsu

    In the healthy heart, muscle cells link together, forming regular structures that pull together to cause the heart to pump. In heart failure, some of these cells die; weakening the heart and making it work harder to get oxygen-rich blood to...