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RESEARCH
Building 3D models of ion channels for drug discoveryUniversity of Leeds | Dr Robin Bon
Ion channels are transporters that allow substances in and out of cells. Ion channels formed of TRPC1, TRPC4 and TRPC5 proteins are involved in several heart and circulatory diseases. It is very important to understand, in enough detail, th...
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RESEARCH
Developing the next generation of troponin testsUniversity of Edinburgh | Professor Nicholas Mills
Edinburgh researchers are striving to improve the detection and diagnosis of heart attack in men and women, and subsequent care afterwards. When the heart is damaged, a protein is released from heart cells. Tests to detect this protein, ...
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Jack Wilshere's Invitational Golf Day raises over £140,000
Former Arsenal and England midfielder, Jack Wilshere, swapped the pitch for the green as he hosted an exclusive Invitational Golf Day in support of us in partnership with Every Minute Matters by Sky Bet. The star-studded day raised an incredible £140,000 to support our lifesaving research.
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6 tips for making healthy meals for one
Our Senior Dietitian shares 6 simple tips for staying healthy and saving money when you live alone. Find out how to make healthy meals for one.
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RESEARCH
The role of cell death in heart failureKing's College London | Professor Kinya Otsu
In the healthy heart, muscle cells link together, forming regular structures that pull together to cause the heart to pump. In heart failure, some of these cells die; weakening the heart and making it work harder to get oxygen-rich blood to...
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RESEARCH
The role of the KCNJ5 potassium channel in blood pressure controlUniversity of Cambridge | Dr Kevin O'Shaughnessy
Up to 10% of people with high blood pressure (hypertension) have an excess of a hormone called aldosterone. Aldosterone is secreted by the adrenal gland and conserves salt in the body, thereby controlling blood pressure. In some people with...
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RESEARCH
Does mutated aquaporin-1 cause pulmonary hypertension?University of Cambridge | Professor Nicholas Morrell
Pulmonary arterial hypertension (PAH) – high blood pressure in the arteries of the lungs – is a rare but incurable condition that leads to heart failure. Several genetic mutations found in people with PAH patients are known to play an impor...
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Can beetroot juice lower blood pressure?
Does beetroot juice lower blood pressure? Read our article to learn more about the nutrition profile of beetroot juice and if it is any good for blood pressure.
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RESEARCH
Von Willebrand factor unfolding the clotting processImperial College London | Professor David A Lane
Following blood vessel injury, platelets are needed to form a blood clot and mend the vessel. Von Willebrand factor (VWF) a ‘sticky’ protein, helps platelets bind to the site of injury. VWF must unfold at the molecular level for this to hap...