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RESEARCH

University College London | Professor Stefan Trapp

Glucagon-like-peptide-1 (GLP-1) is a molecule made by the gut and the brain that reduces appetite and helps control blood sugar levels. Drugs that mimic the effects of GLP-1 are currently used to lower body weight and treat diabetes. Howeve...

A new clinical trial that we've funded could help improve the recovery of children who undergo life-saving heart surgery.

Richard lost his battle with heart failure on his 45th birthday. We hope his story will inspire others to join the fight.

RESEARCH

University of Manchester | Dr Holly Shiels

Short exposures to air pollution can trigger heart attacks, strokes and irregular heart rhythms, especially in people already at risk of these conditions. Evidence suggests a link between a group of air pollutants called polycyclic aromatic...

RESEARCH

University of Oxford | Dr Oliver Rider

Regardless of cause, most heart diseases ultimately result in the heart being unable to pump out as much blood as a normal heart can, because it can’t contract as forcefully. To contract, the heart needs an energy source called ATP, and it’...

Common anti-allergy medicines could prove to be effective treatment for deep vein thrombosis, according to new research we funded.

RESEARCH

University of Bristol | Professor Gianni D Angelini

Heart surgery causes inflammation throughout the whole body, and inflammation is often the reason people stay in intensive care for a long time or even die after surgery. One of the ways the body defends itself against uncontrolled inflamma...

RESEARCH

University of Oxford | Dr Richard Tyser

The heart is the first organ to form in an embryo, and must begin to pump early, but exactly how it first starts to beat is not understood. We know that the beating of the heart is caused by calcium, which moves in and out of cells and tri...

A new NC3Rs & BHF grant will allow scientists at Manchester Metropolitan University to develop a new way to study the formation of dangerous blood clots.

RESEARCH

Newcastle University | Dr Simon Bamforth

Dr Simon Bamforth and colleagues at the University of Newcastle upon Tyne are studying what genes are important during the development of the major blood vessels in the chest, which carry blood to and from the heart, and around the body. Ma...