Search

RESEARCH

How the Piezo1 protein helps endothelial cells respond to stretch

University of Leeds | Professor David Beech

Professor David Beech and colleagues at the University of Leeds have been awarded a PhD studentship to allow a young researcher to study the physical forces within blood vessels. They have shown that a protein called Piezo1, an ion chan...

Can blood thinners lead to heavy periods in the perimenopause?

We explain the link between perimenopause, heavy periods and blood thinners.

RESEARCH

Understanding the molecular changes that could lead to aortic aneurysm

King's College London | Professor Manuel Mayr

Aneurysms are balloon-like bulges that form in blood vessels, for example in the body's main artery in the chest - the aorta. Some aneurysms may stay small but others can burst and be fatal. There are currently no effective treatments for a...

RESEARCH

Attempting to slow down or prevent the development of atherosclerosis

Imperial College London | Professor Justin C Mason

Understanding how atherosclerosis develops and progresses may reveal new ways to prevent or treat the condition in the future. Cells lining the inner wall of our blood vessels are called endothelial cells, or ‘the endothelium’, and are impo...

RESEARCH

How do mutations affecting the nuclear envelope lead to dilated cardiomyopathy?

King's College London | Dr Matthew Stroud

Dilated cardiomyopathy (DCM) is one of the most common forms of inheritable heart disease. It affects the heart muscle, making it stretched and thin so that the heart can’t pump blood around the body efficiently. People with DCM are at risk...

RESEARCH

What tips the balance to cause inflammation in atrial fibrillation?

St George's, University of London | Dr Ingrid Dumitriu

Atrial fibrillation (AF) is the most common form of irregular heart rhythm, affecting more than a million people in the UK. AF interferes with the pumping action of the heart in a way that makes blood clots more likely to form, which can ca...

RESEARCH

Does Ric8B control heartrate in response to the brain’s command?

Queen Mary, University of London | Professor Andrew Tinker

The heart pumps blood round the body and the blood vessels supply oxygen to organs such as brain. This isn't a static system; it needs to be tuned in conditions where there is high demand for oxygen, such as during exercise, and at times wh...

The BHF House of Care programme

Learn about our £1.5 million programme to fund care and support planning via the House of Care framework at five NHS sites in England and Scotland.