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RESEARCH

University of Cambridge | Professor Hugh Markus

Cerebral small vessel disease (SVD) is a disease affecting the small blood vessels of the brain. It can lead to a lacunar stroke – a type of stroke which happens when one of the small blood vessels deep within the brain becomes blocked. ...

RESEARCH

St George's, University of London | Dr Ingrid Dumitriu

Atrial fibrillation (AF) is the most common form of irregular heart rhythm, affecting more than a million people in the UK. AF interferes with the pumping action of the heart in a way that makes blood clots more likely to form, which can ca...

RESEARCH

St George's, University of London | Professor Elijah Behr

Sudden Arrhythmic Death Syndrome (SADS) refers to a sudden and unexpected death where no cause can be identified at post-mortem. It is often caused by one of several rare heart conditions that may run in families. One important cause of S...

RESEARCH

University of Leeds | Professor Peter J Grant

Although blood clotting is an important response to injury, under certain circumstances a blood clot called a thrombus can grow in a blood vessel, blocking the flow of blood and even breaking free from the vessel wall. A thrombus in the cir...

RESEARCH

University of Cambridge | Professor Martin Bennett

BHF Professor Martin Bennett and colleagues at the University of Cambridge are working out if a protein called SIRT6 could be a target for new drugs to treat atherosclerosis, a condition where fatty materials build-up inside arteries. A he...

RESEARCH

University of Birmingham | Dr Katja Gehmlich

The heart responds to repeated exercise and other stresses by becoming bigger in a process known as cardiac hypertrophy. In the inherited disease hypertrophic cardiomyopathy (HCM), hypertrophy is abnormal and takes place in the absence of e...

RESEARCH

University of Leeds | Dr Marc Bailey

Abdominal aortic aneurysm (AAA) is a ballooning of the main blood vessel in the body, the aorta. AAAs tend to grow over time and eventually may rupture, which can be fatal. At the moment, the only treatment is surgery if the aneurysm is lar...

Thanks to 60 years of public support, we’ve become a global leader in funding heart and circulatory disease research, which has helped to improve and save millions of lives. But as the world responds to a pandemic on a scale unseen for a century, we’re having to work harder than ever to protect our life saving work while playing our part in fighting coronavirus (Covid-19).

RESEARCH

University of Leicester | Professor G Andre Ng

Ventricular arrhythmias can lead to sudden cardiac death. There is currently no method of preventing sudden cardiac death, and there is a need to understand the underlying electrical and nervous disruption that causes the abnormal rhythm. T...

RESEARCH

Imperial College London | Dr Kevin Woollard

Dr Kevin Woollard and team at Imperial College London are looking at how dietary fats influence immune cells in the body. It is thought that the body’s own defence system, the immune system, drives the development of atherosclerosis, also c...