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RESEARCH

University College London | Dr Alice Plein

Dr Alice Plein from University College London is studying how the cells lining blood vessels form as embryos develop. She is looking for ways to control new blood vessel growth during heart and circulatory diseases. As the embryo develop...

RESEARCH

University of Leeds | Dr Sreenivasan Ponnambalam

Most heart attacks occur when the coronary arteries, which supply heart muscle with oxygen-rich blood, become narrowed by a gradual build-up of fatty material within their walls. If a piece of fatty material (atheroma) breaks apart it may c...

RESEARCH

University of Manchester | Professor Maciej Tomaszewski

DNA methylation is a chemical modification of DNA that switches off genes. It is an important contributor to heart and circulatory health and diseases. In this project, Professor Tomaszewski and his team will assess DNA methylation in the ...

RESEARCH

University of Glasgow | Dr Martin McBride

Dr Martin McBride and co-workers at the University of Glasgow are investigating the underlying causes of left ventricular hypertrophy, where there is enlargement of the muscle in the left bottom chamber of the heart. Left ventricular hypert...

RESEARCH

University of Manchester | Dr Emmanuel Pinteaux

During a stroke the blood supply to part of the brain is cut off, causing brain cells to become damaged or die. Inflammation – activation of the immune system - is an important defence mechanism that the body uses during injury or infection...

RESEARCH

University of Bristol | Professor Paolo Madeddu

Pericytes are cells that surround blood vessels and play an important role in the growth of new blood vessels (known as angiogenesis). When there is a reduction in blood supply (ischemia), the growth of new blood vessels limits the damage c...

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RESEARCH

University of Glasgow | Professor Keith G Oldroyd

Coronary heart disease is caused by blockage in the coronary arteries - the vessels that supply blood to the heart muscle. Fractional flow reserve (FFR) is a method of measuring pressure waves in the coronary artery to estimate the severity...