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  • RESEARCH

    Sirolimus: A complementary antiplatelet drug?

    University of Bristol | Professor Ingeborg Hers

    Whenever we get a cut or a wound, platelets come together to form a clot and stop the continued bleeding. However, sometimes clots can cause blockages inside the blood vessels, which can eventually cause a heart attack or a stroke. To preve...

  • RESEARCH

    Can genetics help us tailor blood pressure treatment?

    University of Glasgow | Professor Sandosh Padmanabhan

    Professor Sandosh Padmanabhan and colleagues at the University of Glasgow are studying new ways to treat people with uncontrolled hypertension, or high blood pressure. Nearly half of those treated with current blood pressure lowering drugs ...

  • RESEARCH

    Is a molecule called poly ADP ribose involved in blood vessel calcification?

    King's College London | Professor Catherine Shanahan

    Professor Cathy Shanahan is looking for new ways to stop blood vessels accumulating calcium and becoming hard and stiff – a process that can cause high blood pressure and predisposes to coronary heart disease and heart failure. There are cu...

  • RESEARCH

    Finding out how diabetes affects our blood vessels

    University of Oxford | Professor Kim A Dora

    Professor Kim Dora and colleagues from the University of Oxford are interested in how positively charged calcium atoms, known as calcium ions, affect blood vessel narrowing. The level of calcium ions in cells lining the blood vessels co...

  • Britons wardrobe habits revealed

    Nearly a quarter (22%) of Brits feel guilty about the amount of money we spend on our wardrobes, with nearly a fifth (15%) of us lying about our spending sprees to friends and family. BHF have released these new statistics as part of our Spring Clear Out campaign.

  • RESEARCH

    How does insulin like growth factor prevent fatty build-up inside arteries?

    University of Leeds | Dr Stephen Wheatcroft

    Dr Stephen Wheatcroft and his team at the University of Leeds are working out if a hormone called insulin like growth factor-1 (IGF-1) and its receptors can help prevent fatty deposits building up inside the arteries. This 'furring up' ...

  • RESEARCH

    Studying how fats called electrophiles could protect against heart disease

    King's College London | Professor Philip Eaton

    Professor Philip Eaton studies a protein in heart cells and blood vessels called soluble Epoxide Hydrolase, or sEH. Drugs that block this protein have been shown to protect against heart and circulatory disease. During previous research, ...

  • RESEARCH

    Could boosting glucose metabolism treat diabetic cardiomyopathy?

    University of Manchester | Dr Wei Liu

    BHF Intermediate Basic Science Research Fellow Dr Wei Liu is studying ways to treat diabetic cardiomyopathy, a condition that can lead to heart failure because the heart doesn’t pump as well as it should. Healthy hearts are fuelled by a...

  • RESEARCH

    Can a new type of pacemaker treatment improve symptoms in heart failure?

    Imperial College London | Dr Zachary Whinnett

    Dr Zachary Whinnett and his team study heart failure, a serious condition with debilitating symptoms that has no cure. Cardiac resynchronisation therapy (CRT), a type of pacemaker therapy, is an important treatment for heart failure, imp...

  • RESEARCH

    Working out how obesity is a risk factor for blood vessel disease

    University of Oxford | Professor Charalambos Antoniades

    BHF Senior Clinical Research Fellow Professor Charalambos Antoniades is working out why obesity is a risk factor for blood vessel disease, leading to heart attacks and strokes. Fat, or adipose tissue, produces various molecules that hav...