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RESEARCH

New drugs to break the cycle of heart scarring

University of Bristol | Dr Mark Bond

The build-up of scar tissue in the heart (fibrosis) is a key process that contributes to heart failure. It is caused by an increased number of cells called fibroblasts, which lay together to form scar tissue. The result is that the heart wa...

'Heart-in-a-dish' to study the effects of coronavirus

BHF-funded researchers are using stem cell ‘heart-in-a-dish’ technology - originally created to explore potential treatments for heart failure - to help understand how and why coronavirus (Covid-19) impacts the heart.

RESEARCH

Understanding the role of calcium in platelet activation and clotting

University of Birmingham | Dr Michael Tomlinson

Dr Michael Tomlinson from the University of Birmingham is particularly interested in the role of calcium in controlling platelet activity. Although platelets are vital in plugging a site of vessel injury to prevent bleeding, they can also f...

BHF responds to improved ambulance waiting times for heart attacks and strokes

Average ambulance response times for heart attacks and strokes were an hour faster in January than the previous month, new NHS England figures reveal.

RESEARCH

The role of a molecule in endothelial cells and diabetes

King's College London | Dr Anna Zampetaki

King’s College researchers are investigating the role and importance of a molecule seen to be raised in cells in diabetes. More than 4 million people in the UK have diabetes. It is a serious condition with many health consequences, includi...

RESEARCH

Can stem cells help us restore blood flow to the limbs?

University of Bristol | Professor Paolo Madeddu

Peripheral artery disease (PAD) is a common circulatory problem where arteries become narrowed, reducing blood flow to the limbs. Over a quarter of people with critical limb ischemia (CLI), the most advanced form of PAD, are unsuitable for ...

RESEARCH

Can Sulf1 and Sulf2 help to repair a damaged heart?

Royal Veterinary College, University of London | Professor Gurtej K Dhoot

Professor Gurtej Dhoot is working out how two enzymes called Sulf1 and Sulf2 are involved in forming new blood vessels to repair damaged heart muscle. The heart pumps blood containing oxygen and nutrients around the body but also needs i...

RESEARCH

Growing blood vessels to mend the damage caused by a heart attack

Newcastle University | Professor Helen M Arthur

Many thousands of heart attack survivors go on to develop heart failure, a condition which has a detrimental effect on their quality of life. Over recent decades scientists have carried out clinical trials to try to repair damaged hearts us...

Detailed map of the heart provides new insights into heart health and disease

Researchers have produced the most detailed and comprehensive Human Heart Cell Atlas to date including mapping of the specialised cells where the heartbeat originates.