Where to position a pacemaker lead in the heart

 MAPS (Multiparametric CMR for the Assessment of apical versus septal Pacing Study; a randomised crossover design RV multi-site pacing study) 

Matthias Schmitt (lead researcher)

Manchester, University of

Start date: 01 November 2013 (Duration 3 years)

Dr Matthias Schmitt, University of Manchester, is determining the best position for a pacemaker lead in the heart. When a pacemaker is implanted, the lead can be placed at the lowermost tip of the heart, or between the ventricle chambers of the heart. Using Magnetic Resonance Imaging (MRI) and specially designed pacemakers that can function within an MRI machine, Dr Matthias Schmitt is able to take images of the heart as it beats with the pacemakers. MRI can also be used to accurately measure the heart’s pumping function. The heart’s pumping function will be measured over time with both pacemaker lead positions being tested. The capacity of the heart muscle will also be tested using exercise and blood samples will be taken. The blood will be used to measure chemicals that build up when heart muscle comes under stress and subsequently changes its structure.

Project details

Grant amount £91,163
Grant type Fellowship
Application type Clinical Research Training Fellowship
Start Date 01 November 2013
Duration 3 years
Reference FS/13/14/29915
Status Complete

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