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  • RESEARCH

    Understanding how oxidation of a protein called PKGI-alpha regulates the heartbeat

    University of Manchester | Dr Luigi Venetucci

    Each heartbeat consists of two phases: systole and diastole. During systole, heart muscle cells – cardiomyocytes – in the lower chambers of the heart contract (shorten) to pump blood out of the heart. During diastole, these lower chamber ca...

  • RESEARCH

    PKCα: a potential new target to prevent artery calcification

    University of Manchester | Professor Keith Brennan

    Vascular calcification occurs when bone-like deposits build-up in the arteries, causing them to stiffen and narrow. This is a common complication of people with atherosclerosis or kidney disease and can lead to high blood pressure, heart at...

  • RESEARCH

    Refining promising techniques for guiding catheter ablation to stop atrial fibrillation

    University of Leicester | Professor G Andre Ng

    Nearly 1.3 million people in the UK have been diagnosed with Atrial fibrillation (AF), making it the most common heart rhythm disturbance. Symptoms include irregular heartbeats, light-headedness and fatigue, affecting people’s quality of li...

  • RESEARCH

    Making ‘hearts in a dish’ to study myotonic dystrophy

    University of Nottingham | Professor Chris Denning

    Professor Chris Denning and colleagues at the University of Nottingham will use stem cells to investigate how to treat a genetic condition that often leads to death from abnormal heart rhythms, known as myotonic dystrophy. They will take sk...

  • RESEARCH

    The behaviour of BH4 in cardiovascular disease: friend or foe?

    University of Oxford | Professor Keith Channon

    Researchers know that a molecule called BH4 is very important to the circulatory system. However it appears to have two opposing functions. High levels of BH4 in cells that line blood vessels (endothelial cells) protect against disease by h...

  • RESEARCH

    Testing a simple way to get more teenagers active

    Swansea University | Professor Sinead Brophy

    Professor Sinead Brophy and her colleagues at the University of Swansea, in partnership with a local council, are finding out if a simple activity voucher system could help teenagers get active and improve their heart health. Regular exe...

  • RESEARCH

    Hunting for genes linked to cerebral small vessel disease

    University of Cambridge | Professor Hugh Markus

    Professor Hugh Markus and colleagues at the University of Cambridge are studying cerebral small vessel disease (SVD), a disease of the small blood vessels in the brain. The condition causes a quarter of all strokes and underlies vascular de...

  • Heart care waiting list 50% higher than before the pandemic in England

    Latest NHS England figures published today show that the number of people on cardiac waiting lists grew to a record 349,090 at the end of September in England.

  • How to have a healthier afternoon tea

    Afternoon tea is a great winter warmer and some small changes can make it more heart-healthy. Our Senior Dietitian explains how to have your cake, scone or toast

  • £630k research project to determine best treatment after a heart attack

    Nearly 20,000 people in Scotland will be included in a clinical trial to determine the best clot busting drug treatment for people after they have suffered a heart attack.