Psoriasis is a skin disease caused by the immune system. About a third of people with psoriasis develop arthritis, which may affect the hands, feet, knees, and spine. People with psoriatic arthritis are at increased risk of heart attacks, angina and stroke.
Although there may also be lifestyle factors (such as excess weight and low activity levels), increasing the risk of heart disease, inflammation is what links psoriatic arthritis and heart disease. Chronic inflammation can cause direct damage to the blood vessels and heart muscle. It can also accelerate other changes, leading to disease.
Researchers are looking at specific receptors in the heart and brain to help reduce these risks. Other studies are learning about the specific inflammation markers involved and about who can benefit most from early treatment.
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Controlling the immune disease, for example by taking your medication, can reduce your risk of heart problems. But it’s still important to stay vigilant. Tell your GP or dermatologist that you have psoriasis or psoriatic arthritis and that you want a heart health check.
A heart health check includes checking your blood pressure, cholesterol levels, and body mass index. If you’ve already had a heart attack or stroke, your blood pressure and cholesterol need to be carefully managed.
You might be seeing a dermatologist, a cardiologist and rheumatologist, and this can feel challenging. Remember, you’re the owner of your future. It might help to think of yourself as at the centre of a multidisciplinary team.
You can ask about your cardiovascular risk at a dermatology clinic. A way into the conversation is saying: “I’ve been learning about my disease and that I may be at a higher risk of heart problems. Can you tell me more or reassure me?” The specialists should factor these risks into your treatment plan.
Meet the expert
Professor Iain McInnes CBE is a global leader in the field of arthritis research. He is Vice-Principal and Head of College of Medical, Veterinary and Life Sciences at the University of Glasgow. He is Director of the ARUK Centre of Excellence for Rheumatoid Arthritis.
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