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RESEARCH
How do faults in the ryanodine receptor lead to abnormal heart rhythms?Swansea University | Dr Spyros Zissimopoulos
BHF Senior Basic Science Research Fellow Dr Spyros Zissimopoulos is studying a protein involved in the electrical activity of the heart muscle cells that help the heart beat regularly. Dr Zissimopoulos is looking at how defects in the r...
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RESEARCH
Understanding the heart’s protective mechanisms to prevent heart failureKing's College London | Professor Ajay Shah
The focus of most heart failure treatments is to prevent further degeneration of the heart muscle, a process called adverse cardiac remodelling. There is, however, another type of remodelling that is good for the heart. Adaptive remodelling...
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RESEARCH
Predicting and preventing hospitalisation in older people with heart diseaseUniversity of Manchester | Dr Adam Greenstein
Older people with heart disease are more likely to be admitted to hospital, and they often don’t do as well as younger, less frail people with the disease. In this fellowship, the fellow working with Dr Greenstein will investigate whether m...
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RESEARCH
Could ultra-low-dose aspirin reduce side effects and prevent heart attacks?University of Sheffield | Professor Robert Storey
Sheffield researchers will test whether twice-daily low-dose aspirin could be safer than a once-daily standard dose for heart attack prevention. A heart attack occurs when a blood clot blocks a coronary artery feeding the heart. People who...
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RESEARCH
From bug to drug: engineering new heart drugs from tick salivaUniversity of Oxford | Professor Shoumo Bhattacharya
Inflammation plays a role in several heart and circulatory diseases, including myocarditis – inflammation of the heart tissue. It is a very serious condition, which has a poor prognosis and no effective treatment. BHF Professor Shoumo Bhatt...
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RESEARCH
Investigating if MRI scanning can pick up prenatal brain defects in congenital heart diseaseUniversity of Sheffield | Professor Paul Griffiths
Structural problems in the developing heart (congenital heart disease) are amongst the most common birth defects in the UK. Many children with heart defects also have problems with the development of their brain, potentially causing difficu...
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RESEARCH
Understanding how the blood vessels in our heart cope with pressureUniversity of Oxford | Professor Kim A Dora
Blood flow in muscles continually changes depending on whether we are resting or active. To cope with these changes, blood vessels must adapt to meet the demands of rest and exercise. This is especially true in the heart, where vessels are ...