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RESEARCH
Predicting and preventing hospitalisation in older people with heart diseaseUniversity of Manchester | Dr Adam Greenstein
Older people with heart disease are more likely to be admitted to hospital, and they often don’t do as well as younger, less frail people with the disease. In this fellowship, the fellow working with Dr Greenstein will investigate whether m...
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RESEARCH
Understanding how the blood vessels in our heart cope with pressureUniversity of Oxford | Professor Kim A Dora
Blood flow in muscles continually changes depending on whether we are resting or active. To cope with these changes, blood vessels must adapt to meet the demands of rest and exercise. This is especially true in the heart, where vessels are ...
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RESEARCH
Understanding the heart’s protective mechanisms to prevent heart failureKing's College London | Professor Ajay Shah
The focus of most heart failure treatments is to prevent further degeneration of the heart muscle, a process called adverse cardiac remodelling. There is, however, another type of remodelling that is good for the heart. Adaptive remodelling...
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RESEARCH
How do heart muscle proteins change shape when the heart beats?University of Bristol | Dr Danielle Paul
Proteins that make up heart muscle are arranged into structures called filaments. There are two types of filament: thick and thin. A protein called troponin is one of the main components of the thin filament and acts like a switch that turn...
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RESEARCH
Do chemical changes to DNA cause scarring in the heart during coronary heart disease?Queen's University Belfast | Dr Chris Watson
In coronary heart disease, the small vessels that deliver blood supply to the heart are narrowed by the build-up of fatty plaques in the artery wall. These can rupture and cause a blood clot that can completely block the artery. The consequ...
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RESEARCH
Do pre-hospital electrocardiograms increase heart attack survival, and are they used enough?Kingston University London | Professor Tom Quinn
When someone has a suspected heart attack, the ambulance service can test the electrical activity of a person’s the heart to determine the best treatment for them. In a previous project, Professor Tom Quinn and colleagues showed that peo...
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RESEARCH
Cracking the code heart cells use to encourage growth of blood vesselsUniversity of Bristol | Dr Rebecca Richardson
One of the ways the heart repairs itself after a heart attack is by making new blood vessels to restore blood flow to the injured cells as they recover. Damaged cells can send tiny packages, called extracellular vesicles, which contain code...
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RESEARCH
How do omega-3 polyunsaturated fatty acids help to regulate blood pressure?University of Reading | Dr Alister McNeish
Researchers at the University of Reading want to understand exactly how eating oily fish lowers blood pressure. Eating fish or taking fish oil supplements that are high in omega-3 has been shown to improve health. One way that fish oils ...