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RESEARCH

Investigating a new suspect in hypertension

St George's, University of London | Professor Anthony Albert

Nearly 30 per cent of adults in the UK have high blood pressure, which raises the risk of heart disease threefold. Despite how common it is, today’s medicines can fail to tightly control blood pressure in many people. This team in London ar...

RESEARCH

How do heart muscle fibres respond to their environment?

Queen Mary, University of London | Dr Thomas Iskratsch

How do cells know whether they should form heart muscle, a blood vessel or something else? Recent discoveries have shown that one factor influencing heart muscle development is that cells are affected by how rigid their environment is. But ...

RESEARCH

Can a new drug prevent vein graft failure?

University of Bristol | Professor Sarah Jane George

Professor Sarah Jane George and her team at the University of Bristol want to improve the long term success of vein grafts, when a vein is used to bypass a blocked coronary artery in coronary artery bypass. Up to half of vein grafts used in...

RESEARCH

How to encourage people to take their blood pressure tablets

University of Manchester | Professor Maciej Tomaszewski

Professor Maciej Tomaszewski at the University of Manchester wants to find out if a simple, five step intervention can encourage people to take their blood pressure medication properly. High blood pressure, or hypertension, affects near...

RESEARCH

Searching for new treatments to prevent repeat heart attacks or strokes

University of Sheffield | Professor Robert Storey

Supervised by Professor Robert Storey, a Clinical Research Training Fellow is studying how to prevent a further heart attack or stroke in people who have already had a heart attack. Platelets are small circulating cells within the blood t...

RESEARCH

Going inside the heart to make pacemakers benefit more people with heart failure

King's College London | Professor Reza Razavi

Cardiac Resynchronisation Therapy (CRT) is a procedure that’s commonly used in patients with heart failure, which occurs when the heart is not pumping blood around the body as well as it should. This happens most commonly when the heart mus...

RESEARCH

Finding out why exercise causes heart rhythm disturbances in long QT syndrome

Queen Mary, University of London | Professor Andrew Tinker

People with a type of inherited heart condition called long QT syndrome are at risk of abnormal heart rhythms. These abnormal heart rhythms put people at risk of sudden cardiac death, particularly during or following exercise. Long QT syndr...

RESEARCH

Studying why sleep breathing disorders can lead to atrial fibrillation

University of Birmingham | Professor Dr Paulus Kirchhof

Atrial fibrillation (AF) is the most common form of irregular heart rhythm (arrhythmia), sending the top chambers of the heart (the atria) into spasm. AF is dangerous because it significantly increases the likelihood of stroke, so finding e...

RESEARCH

What keeps mitochondria healthy in the heart?

King's College London | Professor Ajay Shah

BHF Professor Ajay Shah and his team at Kings College London are studying whether manipulating a stress pathway in the mitochondria of heart muscle cells could help treat heart disease. Mitochondria are ‘powerhouses’ within cells that gene...