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RESEARCH
Matching heart problems to electrical readings on ECGsImperial College London | Professor Nicholas Peters
Professor Nicholas Peters and his colleagues at Imperial College London are working out how the electrical readings on ECGs (electrocardiograms) relate to underlying heart damage, so that doctors may be better able to diagnose heart problem...
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RESEARCH
Testing a new drug to treat broken heart syndromeUniversity of Aberdeen | Professor Dana Dawson
Supervised by Dr Dana Dawson, this PhD student is investigating a new way to treat a disorder called acute stress-induced (Takotsubo) cardiomyopathy, also known as ‘broken heart’ disease. In broken heart syndrome, stressful situations t...
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RESEARCH
Changes in heart pacemaker cells in ageing and failing heartsUniversity of Manchester | Professor Mark R Boyett
The heartbeat begins at the natural pacemaker of the heart – called the sinoatrial node. The beat is initiated by two systems, called the ‘membrane clock’ and the ‘calcium clock’. As we get older or develop heart failure, the pacemaker no l...
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RESEARCH
A new approach to prevent heart rhythm disorders at the cellular levelCardiff University | Professor Alan Williams
Our heart requires an electrical signal to beat correctly. If this signal breaks down, disturbances in the heart beat rhythm called arrhythmias occur. Some arrhythmias occur because the amount of calcium in the heart muscle cells is abnorma...
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RESEARCH
The link between psychological stress and heart diseaseUniversity College London | Professor Andrew Steptoe
Psychological stress is thought to be linked to the development of coronary heart disease. Stress stimulates vascular inflammation, a process involved in atherosclerosis. But stress also leads to the releases of the hormone cortisol which r...
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RESEARCH
Alternative ways to treat pulmonary hypertensionImperial College London | Professor Ian Adcock
Pulmonary arterial hypertension (PAH) is abnormally high blood pressure in the arteries carrying blood to the lungs, causing damage to the right side of the heart. Symptoms include breathlessness or tiredness. The condition can lead to deat...
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RESEARCH
Can Wnt proteins stop atherosclerotic plaques becoming unstable and rupturing?University of Bristol | Professor Sarah Jane George
Professor Sarah Jane George and her team at the University of Bristol have discovered that a family of proteins called Wnt may be important in keeping fatty atherosclerotic plaques stable. When fatty material builds up on the inner lining o...
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RESEARCH
Cardiac resynchronisation therapy: how it worksImperial College London | Professor Darrel Francis
Cardiac resynchronisation therapy (CRT) involves the implantation of a pacemaker device and is performed in certain heart failure patients to ensure the heartbeat maintains its rhythm. CRT has revolutionised treatment of some forms of heart...
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RESEARCH
Using nanomaterials to lower cholesterolUniversity of Surrey | Dr Daniel Whelligan
Atherosclerosis, where blood vessels become ‘furred up’ and narrowed, is a major cause of death and disability in the UK. Statins are used to lower cholesterol for those with, atherosclerosis but they are not always well tolerated. There ar...