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  • RESEARCH

    Matching heart problems to electrical readings on ECGs

    Imperial College London | Professor Nicholas Peters

    Professor Nicholas Peters and his colleagues at Imperial College London are working out how the electrical readings on ECGs (electrocardiograms) relate to underlying heart damage, so that doctors may be better able to diagnose heart problem...

  • RESEARCH

    Testing a new drug to treat broken heart syndrome

    University of Aberdeen | Professor Dana Dawson

    Supervised by Dr Dana Dawson, this PhD student is investigating a new way to treat a disorder called acute stress-induced (Takotsubo) cardiomyopathy, also known as ‘broken heart’ disease. In broken heart syndrome, stressful situations t...

  • RESEARCH

    Changes in heart pacemaker cells in ageing and failing hearts

    University of Manchester | Professor Mark R Boyett

    The heartbeat begins at the natural pacemaker of the heart – called the sinoatrial node. The beat is initiated by two systems, called the ‘membrane clock’ and the ‘calcium clock’. As we get older or develop heart failure, the pacemaker no l...

  • RESEARCH

    A new approach to prevent heart rhythm disorders at the cellular level

    Cardiff University | Professor Alan Williams

    Our heart requires an electrical signal to beat correctly. If this signal breaks down, disturbances in the heart beat rhythm called arrhythmias occur. Some arrhythmias occur because the amount of calcium in the heart muscle cells is abnorma...

  • RESEARCH

    The link between psychological stress and heart disease

    University College London | Professor Andrew Steptoe

    Psychological stress is thought to be linked to the development of coronary heart disease. Stress stimulates vascular inflammation, a process involved in atherosclerosis. But stress also leads to the releases of the hormone cortisol which r...

  • RESEARCH

    Alternative ways to treat pulmonary hypertension

    Imperial College London | Professor Ian Adcock

    Pulmonary arterial hypertension (PAH) is abnormally high blood pressure in the arteries carrying blood to the lungs, causing damage to the right side of the heart. Symptoms include breathlessness or tiredness. The condition can lead to deat...

  • RESEARCH

    Can Wnt proteins stop atherosclerotic plaques becoming unstable and rupturing?

    University of Bristol | Professor Sarah Jane George

    Professor Sarah Jane George and her team at the University of Bristol have discovered that a family of proteins called Wnt may be important in keeping fatty atherosclerotic plaques stable. When fatty material builds up on the inner lining o...

  • RESEARCH

    Cardiac resynchronisation therapy: how it works

    Imperial College London | Professor Darrel Francis

    Cardiac resynchronisation therapy (CRT) involves the implantation of a pacemaker device and is performed in certain heart failure patients to ensure the heartbeat maintains its rhythm. CRT has revolutionised treatment of some forms of heart...

  • RESEARCH

    Using nanomaterials to lower cholesterol

    University of Surrey | Dr Daniel Whelligan

    Atherosclerosis, where blood vessels become ‘furred up’ and narrowed, is a major cause of death and disability in the UK. Statins are used to lower cholesterol for those with, atherosclerosis but they are not always well tolerated. There ar...