Search

RESEARCH

How a type of immune cell fights against atherosclerosis

University of Cambridge | Professor Ziad Mallat

BHF Professor Ziad Mallat from the University of Cambridge is studying how immune cells are involved in atherosclerosis, a process in which arteries become furred up with fatty plaques and they narrow. If the plaques rupture, they can trigg...

RESEARCH

The link between high blood pressure and a protein called apelin

University of Bristol | Dr Anne Marie O Carroll

Dr Anne-Marie O’Carroll is studying a protein called apelin to work out what role it plays in high blood pressure. High blood pressure, or hypertension, is a major health problem but we don’t fully understand what causes it. Recently the...

RESEARCH

Answering fundamental questions about heart development

University College London | Professor Peter Scambler

Abnormalities in the heart and circulatory system (often called congenital heart disease) are the commonest defects that can be present at birth. Unlocking the genetic secrets behind how the heart develops in the growing embryo may not o...

RESEARCH

What regulates steroid hormone release in tissues? Identifying new mechanisms and therapies for cardiovascular risk

University of Edinburgh | Professor Brian R Walker

Chest pain and heart attacks occur when heart muscle is starved of oxygen as a result of coronary heart disease. The condition develops when arteries to the heart become narrow because of fatty build-up in the artery walls. Many factors inc...

RESEARCH

Tailoring treatments for dangerous abnormal heart rhythms

Swansea University | Professor Christopher George

BHF Professor Alan Williams studies abnormal heart rhythms, or arrhythmias, which can be fatal. Although we understand some of the processes involved in arrhythmias, the efficacy of current treatments are variable, and the causes of abnorma...

RESEARCH

Understanding the role of Pak3 protein in heart cell dysfunction and heart failure

University of Manchester | Dr Wei Liu

Heart failure – when the heart cannot pump blood around the body effectively – is a leading cause of death worldwide. Regardless of the initial cause, many changes take place in heart cells during the development of heart failure. Autopha...

RESEARCH

How do ADAMTS contribute to damaging changes to the extracellular matrix in heart disease?

King's College London | Dr Javier Barallobre Barreiro

Researchers at King’s College London are studying why the mesh of proteins around the heart changes in heart disease. During heart failure the heart can’t pump strongly enough to respond to the demands of the body. It is a life-limiting ...

RESEARCH

Tackling fatty plaques and aneurysms by blocking tiny blood vessel growth.

University of Bristol | Dr Jason L Johnson

Heart attacks occur when a build-up of fatty material in the walls of coronary arteries blocks blood flow to the heart. It’s one of the leading causes of death in the UK. The fatty build-up is known as atherosclerosis, and this can also cau...